Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 12/20 | 0.56 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27810932 | 0.86 | MPL (0.50) | KIF11KCNH2CYP2E1CYP2A6CYP2B6 | |
| SCHEMBL21116892 | 0.82 | KIF11 (0.76) | KIF11CYP11B2CYP11B1 | |
| SCHEMBL2284210 | 0.79 | KCNH2 (0.53) | KCNH2CYP2E1CYP2A6CYP2B6ERN1 | |
| SCHEMBL6120541 | 0.73 | KIF11 (0.69) | KIF11CYP11B2CYP11B1 | |
| SCHEMBL1899073 | 0.72 | ERN1 (0.54) | KCNH2CYP2E1CYP2A6CYP2B6ERN1 | |
| SCHEMBL3896158 | 0.72 | KIF11 (0.72) | KIF11CYP11B2CYP11B1 | |
| SCHEMBL3899619 | 0.72 | KIF11 (1.00) | KIF11CYP11B2CYP11B1 | |
| SCHEMBL3903111 | 0.72 | KIF11 (0.72) | KIF11CYP11B2CYP11B1 | |
| SCHEMBL28184793 | 0.71 | CYP11B2 (0.49) | KIF11CYP11B2CYP11B1 | |
| SCHEMBL2289309 | 0.71 | KIF11 (0.56) | KIF11CYP11B2CYP11B1KCNH2CYP2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109776537-A | Purinedione as WNT pathway modulators | 新加坡科技研究局 | 2019-05-21 | — | — | CN | disclosed |