Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9352308 | 0.81 | TSHR (0.70) | L3MBTL1TDP1LMNAMAPTTBXAS1 | |
| SCHEMBL12854830 | 0.77 | MAPT (0.68) | L3MBTL1TDP1LMNAMAPTHDAC1 | |
| SCHEMBL7752392 | 0.77 | FOLH1 (0.52) | LMNAMAPTTSHRCYP2C19 | |
| SCHEMBL8411357 | 0.77 | TDP1 (0.67) | L3MBTL1TDP1LMNAMAPTHDAC1 | |
| SCHEMBL7068671 | 0.76 | TDP1 (0.95) | L3MBTL1TDP1LMNAMAPTHDAC1 | |
| SCHEMBL6406722 | 0.76 | GRIK1 (0.52) | MAPTTBXAS1HDAC1HDAC2CYP2C19 | |
| SCHEMBL29217264 | 0.76 | MAPT (0.71) | L3MBTL1TDP1LMNAMAPTTBXAS1 | |
| SCHEMBL2745649 | 0.75 | TDP1 (0.64) | L3MBTL1TDP1LMNAMAPTHDAC1 | |
| SCHEMBL9733024 | 0.75 | GRIK1 (0.52) | MAPTTBXAS1TSHRCYP2C19MAPK1 | |
| SCHEMBL9748537 | 0.74 | CYP2C19 (0.50) | TBXAS1CYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109810079-A | A kind of synthetic method of polysubstituted dihydrofuran | 浙江工业大学 | 2019-05-28 | — | — | CN | claimed |
| CN-109810079-A | A kind of synthetic method of polysubstituted dihydrofuran | 浙江工业大学 | 2019-05-28 | — | — | CN | disclosed |