Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | CPA3 | P15088 | 2/20 | 0.45 |
| ▸ | LAP3 | P28838 | 3/20 | 0.44 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.44 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 1/20 | 0.43 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6406722 | 0.87 | GRIK1 (0.52) | CYP2C19GRIK1TBXAS1 | |
| SCHEMBL1748144 | 0.84 | CYP1A2 (0.50) | CYP1A2GRIK1CPA3LAP3ERAP2 | |
| SCHEMBL1857365 | 0.83 | CYP1A2 (0.61) | CYP1A2GRIK1CPA3LAP3ERAP2 | |
| SCHEMBL9007628 | 0.82 | CYP1A2 (0.68) | CYP2C19CYP1A2CPA3CPA1 | |
| SCHEMBL629350 | 0.82 | CYP1A2 (0.68) | CYP2C19CYP1A2CPA3CPA1 | |
| SCHEMBL252900 | 0.82 | CYP1A2 (0.68) | CYP2C19CYP1A2CPA3CPA1 | |
| SCHEMBL10815251 | 0.82 | SMN1; SMN2 (0.49) | — | |
| SCHEMBL10815252 | 0.82 | SMN1; SMN2 (0.49) | — | |
| Water SCHEMBL4010621 | 0.81 | CYP1A2 (0.59) | CYP1A2GRIK1CPA3LAP3ERAP2 | |
| SCHEMBL7439191 | 0.81 | GRIK1 (0.64) | CYP1A2GRIK1CPA3LAP3ERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0192492-B1 | PEPTIDES CONTAINING AN ALIPHATIC-AROMATIC KETONE SIDE CHAIN | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1992-01-02 | — | — | EP | claimed |
| EP-0192492-B1 | PEPTIDES CONTAINING AN ALIPHATIC-AROMATIC KETONE SIDE CHAIN | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1992-01-02 | — | — | EP | disclosed |
| US-4677193-A | GONADOTROPIN-RELEASING FACTOR ANALOGS | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1987-06-30 | — | — | US | disclosed |
| EP-0192492-A2 | Peptides containing an aliphatic-aromatic ketone side chain | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1986-08-27 | — | — | EP | disclosed |