Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.81 |
| ▸ | TP53 | P04637 | 1/20 | 0.81 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.81 |
| ▸ | TSHR | P16473 | 1/20 | 0.81 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.81 |
| ▸ | CDK9 | P50750 | 1/20 | 0.81 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.69 |
| ▸ | RAB9A | P51151 | 6/20 | 0.69 |
| ▸ | NPC1 | O15118 | 5/20 | 0.69 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.69 |
| ▸ | CASP3 | P42574 | 1/20 | 0.68 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.68 |
| ▸ | MAOA | P21397 | 2/20 | 0.65 |
| ▸ | MAOB | P27338 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diphenylurea SCHEMBL133103 | 0.90 | SMN1; SMN2 (1.00) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| Diphenylurea SCHEMBL30786615 | 0.87 | SMN1; SMN2 (0.94) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| Diphenylurea SCHEMBL29392345 | 0.87 | SMN1; SMN2 (0.94) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL11059378 | 0.87 | SMN1; SMN2 (0.94) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| Diphenylurea SCHEMBL3037927 | 0.87 | SMN1; SMN2 (0.94) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| Diphenylurea SCHEMBL28431956 | 0.87 | SMN1; SMN2 (0.94) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL20804375 | 0.83 | SMN1; SMN2 (0.85) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL3460630 | 0.82 | SMN1; SMN2 (0.74) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| Diphenylurea SCHEMBL29504221 | 0.82 | EPHX1 (0.74) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL19501793 | 0.82 | NPC1 (1.00) | SMN1; SMN2TP53EPHX1TSHREPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109776782-B | Ionic organic catalyst and preparation method and application thereof | 华南理工大学 | 2021-02-19 | — | — | CN | disclosed |
| CN-109776782-A | A kind of ionic organic catalyst and its preparation method and application | 华南理工大学 | 2019-05-21 | — | — | CN | disclosed |