Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.94 |
| ▸ | TP53 | P04637 | 1/20 | 0.94 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.94 |
| ▸ | TSHR | P16473 | 1/20 | 0.94 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.94 |
| ▸ | CDK9 | P50750 | 1/20 | 0.94 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.94 |
| ▸ | CASP3 | P42574 | 1/20 | 0.86 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.86 |
| ▸ | MAOA | P21397 | 2/20 | 0.82 |
| ▸ | MAOB | P27338 | 2/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.78 |
| ▸ | RAB9A | P51151 | 7/20 | 0.78 |
| ▸ | NPC1 | O15118 | 6/20 | 0.78 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.78 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.75 |
| ▸ | MAPT | P10636 | 4/20 | 0.72 |
| ▸ | CA12 | O43570 | 1/20 | 0.67 |
| ▸ | CA1 | P00915 | 1/20 | 0.67 |
| ▸ | CA2 | P00918 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diphenylurea SCHEMBL133103 | 0.97 | SMN1; SMN2 (1.00) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| Diphenylurea SCHEMBL29392345 | 0.94 | SMN1; SMN2 (0.94) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| Diphenylurea SCHEMBL30786615 | 0.94 | SMN1; SMN2 (0.94) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| Diphenylurea SCHEMBL28431956 | 0.94 | SMN1; SMN2 (0.94) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| Diphenylurea SCHEMBL3037927 | 0.94 | SMN1; SMN2 (0.94) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL12010916 | 0.93 | CASP3 (1.00) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL30051986 | 0.93 | CASP3 (1.00) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL9479905 | 0.93 | CASP3 (1.00) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL5705930 | 0.91 | MAOA (1.00) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL5359926 | 0.91 | SMN1; SMN2 (0.77) | SMN1; SMN2TP53EPHX1TSHREPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115536554-B | 1,1' - (1, 4-Phenylene) bis (3-phenylurea)/aniline corrosion inhibitor and preparation method and application thereof | 青海师范大学 | 2024-04-26 | — | — | CN | claimed |
| CN-115536554-A | 1,1' - (1, 4-phenylene) bis (3-phenylurea)/aniline corrosion inhibitor and preparation method and application thereof | 青海师范大学 | 2022-12-30 | — | — | CN | claimed |
| US-20250241890-A1 | 1,4-DIUREAS AND 1,4-DITHIOUREAS AND USES THEREOF | PURDUE RESEARCH FOUNDATION | 2025-07-31 | — | — | US | disclosed |
| CN-115536554-B | 1,1' - (1, 4-Phenylene) bis (3-phenylurea)/aniline corrosion inhibitor and preparation method and application thereof | 青海师范大学 | 2024-04-26 | — | — | CN | disclosed |
| CN-115536554-B | 1,1' - (1, 4-Phenylene) bis (3-phenylurea)/aniline corrosion inhibitor and preparation method and application thereof | 青海师范大学 | 2024-04-26 | — | — | CN | disclosed |
| CN-115536554-B | 1,1' - (1, 4-Phenylene) bis (3-phenylurea)/aniline corrosion inhibitor and preparation method and application thereof | 青海师范大学 | 2024-04-26 | — | — | CN | disclosed |
| CN-115536554-A | 1,1' - (1, 4-phenylene) bis (3-phenylurea)/aniline corrosion inhibitor and preparation method and application thereof | 青海师范大学 | 2022-12-30 | — | — | CN | disclosed |
| CN-115536554-A | 1,1' - (1, 4-phenylene) bis (3-phenylurea)/aniline corrosion inhibitor and preparation method and application thereof | 青海师范大学 | 2022-12-30 | — | — | CN | disclosed |
| CN-115536554-A | 1,1' - (1, 4-phenylene) bis (3-phenylurea)/aniline corrosion inhibitor and preparation method and application thereof | 青海师范大学 | 2022-12-30 | — | — | CN | disclosed |
| CN-113773475-B | Catalyst containing bithiophene structure and application thereof in ring-opening polymerization of cyclic ester under light control | 安徽大学 | 2022-06-07 | — | — | CN | disclosed |
| CN-113773475-A | Catalyst containing bithiophene structure and application thereof in ring-opening polymerization of cyclic ester under light control | 安徽大学 | 2021-12-10 | — | — | CN | disclosed |
| US-4444863-A | UREA COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1984-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250241890-A1 | 1,4-DIUREAS AND 1,4-DITHIOUREAS AND USES THEREOF | SNCA, PARK7, SYNCRIP | SMN1; SMN2 14/4885TP53 1480/4885EPHX1 3866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.