Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | PLAT | P00750 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29391322 | 0.81 | TSHR (0.50) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL16740459 | 0.80 | KMT2A (0.46) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL3228479 | 0.77 | CA12 (0.54) | CYP1A2CYP3A4CYP2C19KMT2AMEN1 | |
| SCHEMBL29856945 | 0.77 | MAPT (0.38) | MAPTKDM4EPOLB | |
| SCHEMBL15468562 | 0.76 | BAZ2B (0.54) | CYP1A2CYP3A4CYP2C19KMT2AMEN1 | |
| SCHEMBL15003170 | 0.75 | KMT2A (0.49) | CYP1A2CYP3A4CYP2C19KMT2AMEN1 | |
| SCHEMBL29465035 | 0.75 | JAK2 (0.35) | ALDH1A1PLAT | |
| SCHEMBL1023580 | 0.75 | CLEC4M (0.49) | CYP1A2CYP3A4CYP2C19KMT2AMEN1 | |
| SCHEMBL1126884 | 0.75 | KMT2A (0.44) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL4965511 | 0.74 | GABRA1 (0.56) | CYP1A2CYP3A4CYP2C19KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109790146-B | Pharmaceutical compounds | 阿尔麦克探索有限公司 | 2022-08-23 | — | — | CN | disclosed |
| CN-109790146-A | Medical compounds | 阿尔麦克探索有限公司 | 2019-05-21 | — | — | CN | disclosed |