Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 5/20 | 0.35 |
| ▸ | JAK1 | P23458 | 5/20 | 0.35 |
| ▸ | JAK3 | P52333 | 4/20 | 0.35 |
| ▸ | TYK2 | P29597 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | PDE9A | O76083 | 2/20 | 0.32 |
| ▸ | USP19 | O94966 | 2/20 | 0.32 |
| ▸ | SPR | P35270 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29856945 | 0.80 | MAPT (0.38) | JAK2JAK1JAK3TYK2 | |
| SCHEMBL29856927 | 0.73 | ALDH1A1 (0.34) | SPRALDH1A1KEAP1 | |
| SCHEMBL16126359 | 0.71 | PTGDR2 (0.40) | JAK2JAK1SLC6A4ALDH1A1HTT | |
| SCHEMBL29856971 | 0.71 | CHEK1 (0.37) | PDE9AALDH1A1KEAP1RECQL | |
| SCHEMBL29067807 | 0.71 | JAK2 (0.41) | JAK2JAK1JAK3TYK2 | |
| SCHEMBL16099523 | 0.70 | HPGD (0.46) | SLC6A4ALDH1A1HTT | |
| SCHEMBL22032380 | 0.69 | SMN1; SMN2 (0.58) | USP19ALDH1A1KEAP1 | |
| SCHEMBL31701704 | 0.68 | ALDH1A1 (0.36) | JAK2SLC6A4ALDH1A1NFE2L2 | |
| SCHEMBL31089089 | 0.68 | HTR2A (0.40) | SLC6A4 | |
| Hydrochloric Acid SCHEMBL28822255 | 0.68 | SMN1; SMN2 (0.57) | USP19ALDH1A1KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109790146-B | Pharmaceutical compounds | 阿尔麦克探索有限公司 | 2022-08-23 | — | — | CN | disclosed |