Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28787105 | 0.89 | MAPT (0.53) | GAAMAPTTSHRNPSR1KDM4E | |
| SCHEMBL27398624 | 0.89 | MAPT (0.53) | GAAMAPTTSHRNPSR1KDM4E | |
| SCHEMBL10490158 | 0.84 | MAPT (0.45) | GAAMAPTTSHRNPSR1KDM4E | |
| SCHEMBL12500797 | 0.81 | MAPT (0.51) | GAAMAPTTSHRNPSR1KDM4E | |
| SCHEMBL10833719 | 0.81 | MAPT (0.45) | GAAMAPTTSHRNPSR1KDM4E | |
| SCHEMBL9410025 | 0.80 | MAPT (0.42) | GAAMAPTTSHRNPSR1KDM4E | |
| Hydrochloric Acid SCHEMBL7278125 | 0.79 | TSHR (0.36) | GAAMAPTTSHRNPSR1GRIN2D | |
| SCHEMBL268492 | 0.79 | MAPT (0.53) | GAAMAPTTSHRNPSR1KDM4E | |
| SCHEMBL31650932 | 0.79 | MAPT (0.53) | GAAMAPTTSHRNPSR1KDM4E | |
| SCHEMBL29430156 | 0.79 | MAPT (0.53) | GAAMAPTTSHRNPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109776414-A | A kind of Bcl-2 protein inhibitor and its preparation method and application | 山东大学 | 2019-05-21 | — | — | CN | disclosed |