SCHEMBL28296147

SCHEMBL28296147

CC(C)(C)OC(=O)N(N)S(=O)(=O)C(F)(F)F

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CA14 Q9ULX7 2/20 0.37
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA7 P43166 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC2 Q92769 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28629514 0.75 CA14 (0.31) CA14
SCHEMBL2836502 0.71
SCHEMBL28296347 0.70 CA1 (0.35) CA1CA7
Sulfuric Acid SCHEMBL11537326 0.69 CA14 (0.33) CA14CA12CA1CA7HDAC1
SCHEMBL1706932 0.69 HDAC6 (0.38) CA14CA12CA1CA7HDAC1
SCHEMBL1771686 0.69 HDAC6 (0.38) CA14CA12CA1CA7HDAC1
Trifluoromethanesulfonic Acid SCHEMBL2352815 0.69 CA14 (0.32) CA14
SCHEMBL27633808 0.69 CA14 (0.41) CA14CA12CA1CA7HDAC1
SCHEMBL6049090 0.69 CA1 (0.33) CA1CA7
SCHEMBL1535717 0.68 F2 (0.47) CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109694339-A A kind of novel trifluoromethylthio reagent and its application 天津科技大学 2019-04-30 CN claimed
CN-109694339-A A kind of novel trifluoromethylthio reagent and its application 天津科技大学 2019-04-30 CN disclosed
CN-109694339-A A kind of novel trifluoromethylthio reagent and its application 天津科技大学 2019-04-30 CN disclosed