SCHEMBL28296347

SCHEMBL28296347

NN(C(=O)O)S(=O)(=O)C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
CA13 Q8N1Q1 1/20 0.35
ALDH1A1 P00352 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
F2 P00734 1/20 0.31
PRSS1 P07477 1/20 0.31
PRSS2 P07478 1/20 0.31
PRSS3 P35030 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6049090 0.78 CA1 (0.33) CA1CA2CA7CA13F2
SCHEMBL28296147 0.70 CA14 (0.37) CA1CA7
SCHEMBL3977905 0.69 CA1 (0.44) CA1CA2CA7CA13ALDH1A1
SCHEMBL27433469 0.67
SCHEMBL29194219 0.65 ALDH1A1 (0.30) ALDH1A1L3MBTL1
SCHEMBL24465429 0.65 CA1 (0.40) CA1CA2CA7CA13
SCHEMBL27671263 0.65 CA1 (0.32) CA1CA2CA7
SCHEMBL13791220 0.65 CA1 (0.40) CA1CA2CA7CA13
Hydrochloric Acid SCHEMBL27380209 0.65 CA1 (0.32) CA1CA2CA7
SCHEMBL17882011 0.64 CA1 (0.37) CA1CA2CA7CA13F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109694339-A A kind of novel trifluoromethylthio reagent and its application 天津科技大学 2019-04-30 CN disclosed