Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.41 |
| ▸ | CA12 | O43570 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19285019 | 0.71 | CA14 (0.42) | CA14CA12CA1CA7CA2 | |
| SCHEMBL19285452 | 0.70 | CA12 (0.36) | CA14CA12CA1CA7CA2 | |
| SCHEMBL19284832 | 0.70 | CA12 (0.36) | CA14CA12CA1CA7CA2 | |
| SCHEMBL1706932 | 0.70 | HDAC6 (0.38) | CA14CA12CA1CA7CA2 | |
| SCHEMBL28296147 | 0.69 | CA14 (0.37) | CA14CA12CA1CA7HDAC6 | |
| SCHEMBL27838643 | 0.68 | CA12 (0.37) | CA14CA12CA1CA7CA2 | |
| SCHEMBL14336042 | 0.67 | DGAT1 (0.41) | CA14CA12CA1CA7CA2 | |
| SCHEMBL1025291 | 0.67 | HDAC6 (0.38) | CA14CA12CA1CA7CA2 | |
| SCHEMBL15734005 | 0.67 | NFKB1 (0.44) | CA14CA12CA1CA7HDAC6 | |
| SCHEMBL17276745 | 0.67 | CA14 (0.40) | CA14CA12CA1CA7CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1791596-A | Anti-cancer medicaments | DECIPHERA PHARMACEUTICALS LLC (US) | 2006-06-21 | — | — | CN | disclosed |