SCHEMBL28296240

SCHEMBL28296240

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nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 9/20 0.45
GRIK2 Q13002 4/20 0.45
GRM1 Q13255 1/20 0.45
GRM2 Q14416 1/20 0.45
GRIA4 P48058 2/20 0.44
GRIK3 Q13003 2/20 0.44
GRIK5 Q16478 2/20 0.44
SLC7A5 Q01650 1/20 0.43
GRIA1 P42261 1/20 0.41
GRIA2 P42262 1/20 0.41
PTGS1 P23219 1/20 0.41
SLC7A11 Q9UPY5 1/20 0.41
SLC1A1 P43005 4/20 0.40
GGT1 P19440 3/20 0.40
GSR P00390 1/20 0.40
SLC1A3 P43003 2/20 0.39
SLC1A2 P43004 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28204942 1.00 GRIK1 (0.45) GRIK1GRIK2GRM1GRM2GRIA4
SCHEMBL27399004 0.98 GRIK1 (0.46) GRIK1GRIK2GRM1GRM2GRIA4
Aspartic Acid SCHEMBL28273296 0.91 GRIK1 (0.42) GRIK1GRIK2GRM1GRM2GRIA4
SCHEMBL27955347 0.82 GRIK1 (0.45) GRIK1GRIK2GRM1GRM2GRIA4
SCHEMBL27401897 0.82 GRIK1 (0.45) GRIK1GRIK2GRM1GRM2GRIA4
SCHEMBL7523779 0.81 GRIK1 (0.37) GRIK1GRIK2GRM1GRM2GRIA4
SCHEMBL7780077 0.80 GRIK1 (0.43) GRIK1GRIK2GRM1GRM2GRIA4
SCHEMBL9701317 0.80 GRIK1 (0.45) GRIK1GRIK2GRM1GRM2GRIA4
SCHEMBL17222477 0.80 GRIK1 (0.45) GRIK1GRIK2GRM1GRM2GRIA4
SCHEMBL7781249 0.80 GRIK1 (0.50) GRIK1GRIK2GRM1GRM2GRIA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109912440-A Amino acid type chelated dose of one kind and its method for making in scale and application 南京华狮新材料有限公司 2019-06-21 CN disclosed