SCHEMBL7523779

SCHEMBL7523779

N[C@@H](CC(=O)OC(=O)CCC(=O)C(=O)OC(=O)C[C@H](N)C(=O)O)C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 10/20 0.37
GRIK2 Q13002 4/20 0.37
GRM1 Q13255 2/20 0.37
GRM2 Q14416 2/20 0.37
GRIA4 P48058 5/20 0.37
GRIK3 Q13003 5/20 0.37
GRIK5 Q16478 5/20 0.37
SLC1A1 P43005 3/20 0.37
GRIA2 P42262 4/20 0.35
GRIA1 P42261 3/20 0.35
SLC7A5 Q01650 1/20 0.35
GRM8 O00222 1/20 0.35
GRM6 O15303 1/20 0.35
GRIN2D O15399 1/20 0.35
GRIN3B O60391 1/20 0.35
GSR P00390 1/20 0.35
CYP1A2 P05177 1/20 0.35
GRM5 P41594 1/20 0.35
GRIA3 P42263 1/20 0.35
SLC1A3 P43003 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL148728 0.86 SLC1A1 (0.48) GRIK1GRIK2GRM1GRM2GRIA4
SCHEMBL27399004 0.82 GRIK1 (0.46) GRIK1GRIK2GRM1GRM2GRIA4
SCHEMBL28296240 0.81 GRIK1 (0.45) GRIK1GRIK2GRM1GRM2GRIA4
SCHEMBL28204942 0.81 GRIK1 (0.45) GRIK1GRIK2GRM1GRM2GRIA4
SCHEMBL27651609 0.79 GRIK1 (0.54) GRIK1GRIK2GRM1GRM2GRIA4
Aspartic Acid SCHEMBL28273296 0.77 GRIK1 (0.42) GRIK1GRIK2GRM1GRM2GRIA4
SCHEMBL27815508 0.76 GSR (0.47) GRIK1GRIK2GRM1GRM2GRIA4
SCHEMBL28225380 0.76
SCHEMBL693114 0.75 GRIK1 (0.44) GRIK1GRIK2GRM1GRM2GRIA4
SCHEMBL9817851 0.75 GRIK1 (0.44) GRIK1GRIK2GRM1GRM2GRIA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106868066-A The method for producing the microorganism of O acetylhomoserines and O acetylhomoserines being produced using the microorganism CJ第制糖株式会社 2017-06-20 CN disclosed
CN-103797027-B Variant polypeptide having homoserine acetyltransferase activity and microorganism expressing same CJ 第制糖株式会社 2017-05-17 CN disclosed
CN-104911136-A Microorganism producing O-acetyl-homoserine and the method of producing O-acetyl-homoserine using the microorganism CJ CHEILJEDANG CORP 2015-09-16 CN disclosed
EP-1172439-A1 THERMOSTABLE ENZYME HAVING AMINOTRANSFERASE ACTIVITY AND GENE ENCODING THE SAME National Institute of Advanced Industrial Science and Technology (JP) 2002-01-16 EP disclosed