Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
| ▸ | GPR27 | Q9NS67 | 4/20 | 0.38 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28294692 | 0.91 | MEN1 (0.39) | MEN1MAPTKMT2ARAB9AHTT | |
| SCHEMBL28296314 | 0.80 | MAOB (0.44) | MEN1MAPTKMT2ARAB9ALMNA | |
| SCHEMBL28571714 | 0.77 | GPR27 (0.55) | MEN1MAPTKMT2ARAB9AHTT | |
| SCHEMBL28576258 | 0.74 | JAK2 (0.52) | MEN1MAPTKMT2ARAB9AHTT | |
| SCHEMBL28417758 | 0.73 | GRIN1 (0.43) | MEN1KMT2AMAOBCYP1A1CYP1B1 | |
| SCHEMBL28417757 | 0.73 | GRIN1 (0.43) | MEN1KMT2AMAOBCYP1A1CYP1B1 | |
| SCHEMBL28294691 | 0.73 | GRIN1 (0.43) | MEN1KMT2AMAOBCYP1A1CYP1B1 | |
| SCHEMBL28415675 | 0.70 | RAB9A (0.57) | MEN1MAPTKMT2ARAB9AHTT | |
| SCHEMBL16400445 | 0.69 | MAOB (0.46) | MAPTRAB9AMAOBCYP1A1CYP1B1 | |
| SCHEMBL16400448 | 0.69 | MAOB (0.46) | MAPTRAB9AMAOBCYP1A1CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109796372-A | A method of preparing polysubstituted alkenyl amidine | 中国科学院化学研究所 | 2019-05-24 | — | — | CN | disclosed |