Benzene

Benzene

SCHEMBL28296352

c1cc2sccc2[nH]1.c1ccccc1.c1ccsc1

nearest known ligand 0.35

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Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.35
TRPA1 O75762 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
ITGB2 P05107 1/20 0.31
ICAM1 P05362 1/20 0.31
ITGAL P20701 1/20 0.31
CA4 P22748 1/20 0.31
CA6 P23280 1/20 0.31
AHR P35869 1/20 0.31
ADK P55263 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL220723 0.87
SCHEMBL2156749 0.85
SCHEMBL15577215 0.79 DAO (0.37) DAO
Benzothiophene SCHEMBL28556052 0.77 TRPA1 (0.42) DAOTRPA1CA1CA2ITGB2
Indole SCHEMBL27986465 0.74 AHR (0.59) TRPA1CA1CA2ITGB2ICAM1
Benzene SCHEMBL27958890 0.73 GPR35 (0.37) DAO
SCHEMBL7627620 0.71 TRPA1 (0.38) TRPA1CA1CA2ITGB2ICAM1
Thiophene SCHEMBL716369 0.70 GPR35 (0.33)
Thiophene SCHEMBL15754567 0.70 GPR35 (0.33)
Pyrrole SCHEMBL29290733 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109880067-A One kind is containing double cable conjugated polymers of benzene thiophene-Thienopyrroles diketone type and preparation method thereof 江西省科学院应用化学研究所 2019-06-14 CN claimed
CN-109880067-A One kind is containing double cable conjugated polymers of benzene thiophene-Thienopyrroles diketone type and preparation method thereof 江西省科学院应用化学研究所 2019-06-14 CN disclosed
CN-109880067-A One kind is containing double cable conjugated polymers of benzene thiophene-Thienopyrroles diketone type and preparation method thereof 江西省科学院应用化学研究所 2019-06-14 CN disclosed
CN-109880067-A One kind is containing double cable conjugated polymers of benzene thiophene-Thienopyrroles diketone type and preparation method thereof 江西省科学院应用化学研究所 2019-06-14 CN disclosed