Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | HTR1D | P28221 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR1E | P28566 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL547396 | 0.83 | ALDH1A1 (0.65) | ALDH1A1LMNAHTTMAPTHTR1A | |
| Quinoline SCHEMBL27740770 | 0.82 | ALDH1A1 (0.49) | ALDH1A1POLBMAPTHTR2AKMT2A | |
| Tryptamine SCHEMBL28456625 | 0.80 | HTR6 (0.68) | ALDH1A1POLBMAPTHTR1AHTR1D | |
| Quinoline SCHEMBL27558601 | 0.79 | BCHE (0.42) | ALDH1A1LMNAHTTPOLBMAPT | |
| Quinoline SCHEMBL27471421 | 0.75 | ATM (0.62) | ALDH1A1LMNAMAPTKMT2AMEN1 | |
| 3-Formylindole SCHEMBL27819977 | 0.74 | CYP2A6 (0.66) | ALDH1A1LMNAHTTMAPTKMT2A | |
| Quinoline SCHEMBL28872941 | 0.74 | NPC1 (0.50) | ALDH1A1LMNAHTTPOLBMAPT | |
| Quinoline SCHEMBL28128642 | 0.73 | ALDH1A1 (0.47) | ALDH1A1HTTPOLBMAPTKMT2A | |
| Quinoline SCHEMBL28833127 | 0.72 | ALDH1A1 (0.50) | ALDH1A1LMNAPOLBMAPTHTR1A | |
| Quinoline SCHEMBL27276065 | 0.72 | ALDH1A1 (0.50) | ALDH1A1LMNAPOLBMAPTHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109912488-A | The method that copper catalysis disactivation olefin alkylation is combined to 3- alkyl-indol quinoline | 昆明学院 | 2019-06-21 | — | — | CN | claimed |
| CN-109912488-A | The method that copper catalysis disactivation olefin alkylation is combined to 3- alkyl-indol quinoline | 昆明学院 | 2019-06-21 | — | — | CN | disclosed |
| CN-109912488-A | The method that copper catalysis disactivation olefin alkylation is combined to 3- alkyl-indol quinoline | 昆明学院 | 2019-06-21 | — | — | CN | disclosed |
| CN-109912488-A | The method that copper catalysis disactivation olefin alkylation is combined to 3- alkyl-indol quinoline | 昆明学院 | 2019-06-21 | — | — | CN | disclosed |