Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD3 | Q15059 | 2/20 | 0.47 |
| ▸ | HPGDS | O60760 | 2/20 | 0.47 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.44 |
| ▸ | TUBB | P07437 | 2/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.44 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.44 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14540708 | 0.77 | GPR119 (0.48) | HPGDSSSTR3NAMPTGPR119KDM4E | |
| SCHEMBL26837525 | 0.76 | HPGDS (0.47) | BRD3HPGDSSSTR3TUBB4ATUBB | |
| SCHEMBL19952634 | 0.76 | TLR8 (0.47) | BRD3NAMPTGPR119KDM4EMAPT | |
| SCHEMBL29584028 | 0.76 | TLR8 (0.47) | BRD3NAMPTGPR119KDM4EMAPT | |
| SCHEMBL19297081 | 0.75 | EED (0.49) | NAMPTGPR119KDM4EMAPTTHRB | |
| SCHEMBL557776 | 0.74 | KDM4E (0.70) | GPR119KDM4EMAPTTHRBJAK2 | |
| SCHEMBL25036983 | 0.74 | DDB1 (0.51) | HPGDSSSTR3NAMPTGPR119KDM4E | |
| SCHEMBL7893351 | 0.74 | PROKR1 (0.55) | BRD3HPGDSSSTR3GPR119JAK2 | |
| SCHEMBL30736677 | 0.74 | EED (0.53) | NAMPTGPR119KDM4EMAPTTHRB | |
| SCHEMBL922043 | 0.74 | EED (0.53) | NAMPTGPR119KDM4EMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109923108-A | Pyridyl-substituted indole compounds | 百时美施贵宝公司 | 2019-06-21 | — | — | CN | disclosed |