SCHEMBL28296540

SCHEMBL28296540

C=CCNc1ccccc1.[AlH3]

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.52
CA2 P00918 2/20 0.52
CA9 Q16790 2/20 0.52
CA1 P00915 1/20 0.52
ALDH1A1 P00352 4/20 0.46
MAPT P10636 2/20 0.46
CYP1A2 P05177 1/20 0.44
TGM2 P21980 1/20 0.43
KMT2A Q03164 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
RAB9A P51151 2/20 0.42
KDM4E B2RXH2 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
MEN1 O00255 1/20 0.42
GAA P10253 1/20 0.42
HPGD P15428 1/20 0.42
MITF O75030 1/20 0.42
NSD2 O96028 1/20 0.42
LMNA P02545 1/20 0.42
CASP3 P42574 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11051 0.98 CA12 (0.53) CA12CA2CA9CA1ALDH1A1
SCHEMBL16371883 0.98 CA12 (0.53) CA12CA2CA9CA1ALDH1A1
SCHEMBL253353 0.95 CA12 (0.52) CA12CA2CA9CA1ALDH1A1
SCHEMBL10385905 0.95 CA12 (0.52) CA12CA2CA9CA1ALDH1A1
Iodide SCHEMBL11631405 0.95 CA12 (0.52) CA12CA2CA9CA1ALDH1A1
Water SCHEMBL10657216 0.95 CA12 (0.52) CA12CA2CA9CA1ALDH1A1
Hydrochloric Acid SCHEMBL728400 0.95 CA12 (0.52) CA12CA2CA9CA1ALDH1A1
Cyanide SCHEMBL29655773 0.91 CA12 (0.48) CA12CA2CA9CA1ALDH1A1
SCHEMBL821094 0.89 ALDH1A1 (0.54) CA12CA2CA9CA1ALDH1A1
SCHEMBL27549272 0.87 CA12 (0.46) CA12CA2CA9CA1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109705159-A A kind of preparation method and application of phosphorous nitrogen ligand alkyl aluminum compound 青岛科技大学 2019-05-03 CN claimed