Hydrochloric Acid

Hydrochloric Acid

SCHEMBL728400

C=CCNc1ccccc1.Cl

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 known ✓ P00918 2/20 0.52
GAA known ✓ P10253 1/20 0.42
CA12 O43570 2/20 0.52
CA9 Q16790 2/20 0.52
CA1 P00915 1/20 0.52
ALDH1A1 P00352 4/20 0.46
MAPT P10636 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.45
CYP1A2 P05177 1/20 0.44
TGM2 P21980 1/20 0.43
KMT2A Q03164 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
RAB9A P51151 2/20 0.42
KDM4E B2RXH2 2/20 0.42
MEN1 O00255 1/20 0.42
HPGD P15428 1/20 0.42
MITF O75030 1/20 0.42
NSD2 O96028 1/20 0.42
LMNA P02545 1/20 0.42
CASP3 P42574 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11051 0.98 CA12 (0.53) CA12CA2CA9CA1ALDH1A1
SCHEMBL16371883 0.98 CA12 (0.53) CA12CA2CA9CA1ALDH1A1
SCHEMBL253353 0.95 CA12 (0.52) CA12CA2CA9CA1ALDH1A1
SCHEMBL28296540 0.95 CA12 (0.52) CA12CA2CA9CA1ALDH1A1
Iodide SCHEMBL11631405 0.95 CA12 (0.52) CA12CA2CA9CA1ALDH1A1
Water SCHEMBL10657216 0.95 CA12 (0.52) CA12CA2CA9CA1ALDH1A1
SCHEMBL10385905 0.95 CA12 (0.52) CA12CA2CA9CA1ALDH1A1
Cyanide SCHEMBL29655773 0.91 CA12 (0.48) CA12CA2CA9CA1ALDH1A1
SCHEMBL821094 0.89 ALDH1A1 (0.54) CA12CA2CA9CA1ALDH1A1
SCHEMBL27549272 0.87 CA12 (0.46) CA12CA2CA9CA1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 501 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104918589-B Antimicrobial non-adhesive dressing and associated method of use COVIDIEN L.P. (US) 2019-11-01 CN claimed
CN-104884198-B The method for preparing the hollow metal nanometer particle being supported on carrier LG化学株式会社 2017-11-17 CN claimed
CN-103857484-B The method preparing hollow metal nanometer particle and the hollow metal nanometer particle prepared by the method LG化学株式会社 2016-06-08 CN claimed
CN-104918589-A Antimicrobial non-adherent dressings and related methods therefor COVIDIEN LP 2015-09-16 CN claimed
CN-104884198-A Method for manufacturing hollow metal nanoparticle supported by support body LG CHEMICAL LTD 2015-09-02 CN claimed
CN-103857484-A Method for manufacturing hollow metal nanoparticles, and hollow metal nanoparticles manufactured thereby LG CHEMICAL LTD 2014-06-11 CN claimed
CN-101987909-B Processes for producing polyester latexes via solvent-free emulsification XEROX CORP 2013-11-06 CN claimed
CN-103102495-A Powder coated carrier XEROX CORP 2013-05-15 CN claimed
CN-101987909-A Processes for producing polyester latexes via solvent-free emulsification XEROX CORP 2011-03-23 CN claimed
CN-101879140-A The nanoparticle and the sustained release compositions that comprise aryl-heterocyclic compounds ELAN PHARMA INT LTD 2010-11-10 CN claimed
CN-101237868-A Nanoparticulate clopidogrel and aspirin combination formulations ELAN PHARMA INT LTD (IE) 2008-08-06 CN claimed
CN-101212954-A Nanoparticulate clopidogrel formulations ELAN PHARMA INT LTD (IE) 2008-07-02 CN claimed
CN-101198314-A Nanoparticulate quinazoline derivative formulations ELAN PHARMA INT LTD (IE) 2008-06-11 CN claimed
CN-101198316-A Nanoparticulate bisphosphonate compositions ELAN PHARMA INT LTD (IE) 2008-06-11 CN claimed
CN-101180038-A Nanoparticulate corticosteroid and antihistamine formulations ELAN PHARMA INT LTD (IE) 2008-05-14 CN claimed
CN-101175480-A Nanoparticulate leukotriene receptor antagonist/corticosteroid formulations ELAN PHARMA INT LTD (IE) 2008-05-07 CN claimed
CN-101175481-A Injectable compositions of nanoparticulate immunosuppressive compounds ELAN PHARMA INT LTD (IE) 2008-05-07 CN claimed
CN-101160118-A Nanoparticulate formulations of docetaxel and analogues thereof ELAN PHARMA INT LTD (IE) 2008-04-09 CN claimed
CN-101132770-A Nanoparticulate candesartan formulations ELAN PHARMA INT LTD (IE) 2008-02-27 CN claimed
CN-101090720-A Nanoparticulate compositions of tubulin inhibitor compounds BAXTER INT (US) 2007-12-19 CN claimed