Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28236513 | 0.82 | SLC6A1 (0.36) | KMT2AMEN1TSHR | |
| Bromide SCHEMBL5330231 | 0.67 | MEN1 (0.61) | KMT2AMEN1TSHR | |
| SCHEMBL28180334 | 0.67 | KDM4E (0.33) | KMT2AKDM4EMAPTATMCYP2D6 | |
| SCHEMBL10362925 | 0.63 | KDM4E (0.34) | KMT2AKDM4E | |
| Iodide SCHEMBL22031617 | 0.63 | — | — | |
| Hydrochloric Acid SCHEMBL22031619 | 0.63 | — | — | |
| SCHEMBL2919226 | 0.61 | KDM4E (0.67) | KMT2AKDM4EMAPTATMCYP2D6 | |
| Hydrochloric Acid SCHEMBL28525881 | 0.60 | KDM4E (0.64) | KMT2AKDM4EMAPTATMCYP2D6 | |
| SCHEMBL14009727 | 0.58 | EPHX1 (0.54) | KMT2AKDM4EMAPTATMCYP2D6 | |
| SCHEMBL13986885 | 0.58 | EPHX1 (0.54) | KMT2AKDM4EMAPTATMCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109843856-A | KRAS G12C inhibitor | 米拉蒂治疗股份有限公司 | 2019-06-04 | — | — | CN | disclosed |