Nitrobenzene

Nitrobenzene

SCHEMBL28296712

N#N.Nc1ccccn1.O=[N+]([O-])c1ccccc1

nearest known ligand 0.55

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.55
LMNA P02545 3/20 0.55
NOS3 P29474 1/20 0.55
NOS1 P29475 1/20 0.55
NOS2 P35228 1/20 0.55
PI4KA P42356 1/20 0.55
PI4K2B Q8TCG2 1/20 0.55
PI4K2A Q9BTU6 1/20 0.55
PI4KB Q9UBF8 1/20 0.55
NPC1 O15118 6/20 0.44
RAB9A P51151 6/20 0.44
MAPT P10636 5/20 0.44
KDM4E B2RXH2 2/20 0.43
MAPK1 P28482 1/20 0.43
HTT P42858 1/20 0.43
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
PDE4D Q08499 1/20 0.42
GPR35 Q9HC97 1/20 0.42
F12 P00748 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Aminopyridine SCHEMBL28035454 0.79
Nitrobenzene SCHEMBL111513 0.79 ALDH1A1 (0.89) ALDH1A1LMNANPC1RAB9AMAPT
2-Aminopyridine SCHEMBL28654841 0.79
Nitrobenzene SCHEMBL28020847 0.77 ALDH1A1 (0.84) ALDH1A1LMNANPC1RAB9AMAPT
Nitrobenzene SCHEMBL5565885 0.77 ALDH1A1 (0.84) ALDH1A1LMNANPC1RAB9AMAPT
Nitrobenzene SCHEMBL29187628 0.77 ALDH1A1 (0.84) ALDH1A1LMNANPC1RAB9AMAPT
2-Aminopyridine SCHEMBL10923877 0.77 NOS3 (0.94) LMNANOS3NOS1NOS2PI4KA
Nitrobenzene SCHEMBL3237422 0.75 ALDH1A1 (0.73) ALDH1A1LMNANPC1RAB9AMAPT
Nitrobenzene SCHEMBL11050641 0.74 ALDH1A1 (0.89) ALDH1A1LMNAMAPK1MEN1KMT2A
Nitrobenzene SCHEMBL897631 0.74 ALDH1A1 (0.89) ALDH1A1LMNAMAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109839374-A The screening technique of total cadmium content in a kind of fabric coating 上海市质量监督检验技术研究院 2019-06-04 CN disclosed
CN-109839374-A The screening technique of total cadmium content in a kind of fabric coating 上海市质量监督检验技术研究院 2019-06-04 CN disclosed