Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.45 |
| ▸ | PGK1 | P00558 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.35 |
| ▸ | CSK | P41240 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.35 |
| ▸ | CAMK1G | Q96NX5 | 1/20 | 0.35 |
| ▸ | CCR4 | P51679 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.33 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28296733 | 1.00 | TRPM8 (0.45) | TRPM8PGK1IDO1SMN1; SMN2MITF | |
| SCHEMBL22805390 | 0.83 | TLR7 (0.43) | TRPM8TLR8TLR7 | |
| SCHEMBL17123639 | 0.82 | TLR7 (0.51) | TRPM8TLR8TLR7 | |
| SCHEMBL13769046 | 0.81 | MEN1 (0.44) | PGK1IDO1RPS6KB1BTKTLR8 | |
| SCHEMBL1442231 | 0.79 | TRPM8 (0.54) | TRPM8PGK1SMN1; SMN2MITFLMNA | |
| SCHEMBL20652469 | 0.79 | STK17A (0.36) | PGK1IDO1RPS6KB1CCR4STK17A | |
| SCHEMBL13195718 | 0.77 | STK17A (0.49) | PGK1SMN1; SMN2L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL13195752 | 0.75 | TLR7 (0.49) | TRPM8SMN1; SMN2MITFLMNAMAPT | |
| SCHEMBL1937502 | 0.74 | TLR8 (0.41) | PGK1L3MBTL1ALDH1A1STK17ATLR8 | |
| SCHEMBL1442559 | 0.73 | PGK1 (0.51) | PGK1SMN1; SMN2KDM4EALDH1A1STK17A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109790154-A | Pyrimidine prodrugs for the treatment of viral infections and additional diseases | 爱尔兰詹森科学公司 | 2019-05-21 | — | — | CN | disclosed |