Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ATP4A | P20648 | 1/20 | 0.34 |
| ▸ | ATP4B | P51164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL28833083 | 1.00 | TDP1 (0.39) | TDP1TSHRNAPRTNPSR1MEN1 | |
| Pyridine SCHEMBL1560514 | 0.96 | TDP1 (0.43) | TDP1TSHRNAPRTNPSR1MEN1 | |
| Pyridine SCHEMBL15019090 | 0.89 | KCNH2 (0.41) | TDP1TSHRNAPRTNPSR1MEN1 | |
| Pyridine SCHEMBL28135868 | 0.89 | DNM1 (0.45) | TSHRMEN1KMT2AALDH1A1KCNH2 | |
| Pyridine SCHEMBL28085759 | 0.86 | MAPT (0.37) | TDP1TSHRNAPRTNPSR1MEN1 | |
| Pyridine SCHEMBL28093266 | 0.81 | TSHR (0.47) | TDP1TSHRNAPRTDRD2OPRM1 | |
| Benzene SCHEMBL27562059 | 0.81 | MEN1 (0.48) | TDP1NPSR1MEN1KMT2AMAPT | |
| Pyridine SCHEMBL27859626 | 0.79 | TSHR (0.45) | TDP1TSHRNAPRTDRD2OPRM1 | |
| Benzene SCHEMBL7769018 | 0.78 | MEN1 (0.47) | TDP1NPSR1MEN1KMT2AMAPT | |
| Hexane SCHEMBL5964926 | 0.78 | TSHR (0.56) | TDP1TSHRNAPRTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109803977-A | NUCLEIC ACID PRODUCTS AND METHODS OF ADMINISTRATION THEREOF | 菲克特生物科学股份有限公司 | 2019-05-24 | — | — | CN | disclosed |