Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 3/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | ICMT | O60725 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
| ▸ | S100A4 | P26447 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL1560514 | 0.90 | TDP1 (0.43) | MAPTALDH1A1POLBNPSR1MEN1 | |
| Pyridine SCHEMBL28296747 | 0.86 | TDP1 (0.39) | MAPTALDH1A1POLBNPSR1MEN1 | |
| Pyridine SCHEMBL28833083 | 0.86 | TDP1 (0.39) | MAPTALDH1A1POLBNPSR1MEN1 | |
| Pyridine SCHEMBL15019090 | 0.84 | KCNH2 (0.41) | MAPTALDH1A1NPSR1MEN1KMT2A | |
| Pyridine SCHEMBL28879602 | 0.81 | TSHR (0.53) | MAPTALDH1A1POLBMEN1KMT2A | |
| Pyridine SCHEMBL28093266 | 0.77 | TSHR (0.47) | TSHRNAPRTTDP1DRD2OPRM1 | |
| Pyridine SCHEMBL28135868 | 0.77 | DNM1 (0.45) | ALDH1A1MEN1KMT2ATSHRKCNH2 | |
| Benzene SCHEMBL27562059 | 0.76 | MEN1 (0.48) | MAPTNPSR1MEN1KMT2ATDP1 | |
| Pyridine SCHEMBL22352697 | 0.75 | ICMT (0.41) | ALDH1A1DRD2DRD3ICMTALB | |
| Pyridine SCHEMBL27859626 | 0.74 | TSHR (0.45) | TSHRNAPRTTDP1DRD2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103087133-B | Purine derivative is as adenosine A1receptor stimulating agent and usage thereof | 伊诺泰克制药公司 | 2016-09-14 | — | — | CN | disclosed |