Toluene

Toluene

SCHEMBL28296748

CCCCCCCCOC(=O)CCCCC(=O)OCCCCCCCC.Cc1ccccc1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.61
TSHR P16473 2/20 0.55
LMNA P02545 2/20 0.55
ALDH1A1 P00352 2/20 0.55
TP53 P04637 1/20 0.53
CYP3A4 P08684 1/20 0.53
MAPK1 P28482 1/20 0.53
PRSS1 P07477 1/20 0.52
PRSS2 P07478 1/20 0.52
PRSS3 P35030 1/20 0.52
PAM P19021 2/20 0.51
NAAA Q02083 1/20 0.51
DNM1 Q05193 1/20 0.51
EPHX2 P34913 2/20 0.51
HTR2C P28335 1/20 0.50
KDM4E B2RXH2 1/20 0.49
POLB P06746 1/20 0.49
HSD17B10 Q99714 1/20 0.49
PPARG P37231 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL4749551 0.90 CYP4F2 (0.55) DGKATSHRALDH1A1PAM
Toluene SCHEMBL6270207 0.90 CYP4F2 (0.55) DGKATSHRALDH1A1PAM
Toluene SCHEMBL10334155 0.90 DGKA (0.51) DGKATSHRLMNAALDH1A1CYP3A4
O-Xylene SCHEMBL31519872 0.89 DGKA (0.62) DGKATSHRLMNAALDH1A1TP53
Benzene SCHEMBL9957260 0.88 DGKA (0.77) DGKATSHRLMNAALDH1A1PRSS1
Benzene SCHEMBL11441206 0.88 DGKA (0.77) DGKATSHRLMNAALDH1A1PRSS1
Toluene SCHEMBL9169396 0.88 DGKA (0.48) DGKATSHRLMNAALDH1A1TP53
P-Xylene SCHEMBL6536586 0.87 DGKA (0.75) DGKATSHRLMNAALDH1A1PRSS1
P-Xylene SCHEMBL15987887 0.87 DGKA (0.75) DGKATSHRLMNAALDH1A1PRSS1
Ethylene Glycol Dioctanoate SCHEMBL15987600 0.87 DGKA (0.75) DGKATSHRLMNAALDH1A1PRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109694323-A The synthetic method of organic drug intermediate dioctyl adipate 张欣 2019-04-30 CN claimed
CN-109694323-A The synthetic method of organic drug intermediate dioctyl adipate 张欣 2019-04-30 CN disclosed
CN-109694323-A The synthetic method of organic drug intermediate dioctyl adipate 张欣 2019-04-30 CN disclosed