Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.75 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.57 |
| ▸ | PAM | P19021 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| P-Xylene SCHEMBL15988059 | 1.00 | DGKA (0.75) | DGKADNM1PAMTSHRMAPT | |
| Ethylene Glycol Dioctanoate SCHEMBL15987600 | 1.00 | DGKA (0.75) | DGKADNM1PAMTSHRMAPT | |
| P-Xylene SCHEMBL15987620 | 1.00 | DGKA (0.75) | DGKADNM1PAMTSHRMAPT | |
| P-Xylene SCHEMBL15987887 | 1.00 | DGKA (0.75) | DGKADNM1PAMTSHRMAPT | |
| SCHEMBL12768699 | 0.89 | DGKA (0.59) | DGKATSHRPRSS1PRSS2PRSS3 | |
| SCHEMBL13933190 | 0.89 | DGKA (0.59) | DGKATSHRPRSS1PRSS2PRSS3 | |
| SCHEMBL13612295 | 0.89 | DGKA (0.59) | DGKATSHRPRSS1PRSS2PRSS3 | |
| SCHEMBL13854770 | 0.87 | DGKA (0.57) | DGKATSHRLMNAALDH1A1MEN1 | |
| P-Xylene SCHEMBL9305936 | 0.87 | DGKA (0.56) | DGKADNM1PAMPRSS1PRSS2 | |
| SCHEMBL813087 | 0.87 | DGKA (1.00) | DGKADNM1PAMTSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2772523-B1 | REVERSIBLY THERMOCHROMIC COMPOSITION | PILOT CORPORATION KK (JP) | 2018-11-28 | — | — | EP | disclosed |
| US-20140291585-A1 | REVERSIBLY THERMOCHROMIC COMPOSITION | KABUSHIKI KAISHA PILOT CORPORATION (JP) | 2014-10-02 | — | — | US | disclosed |
| EP-2772523-A1 | REVERSIBLY THERMOCHROMIC COMPOSITION | Kabushiki Kaisha Pilot Corporation (JP) | 2014-09-03 | — | — | EP | disclosed |
| US-6828070-B2 | Heat sensitive element | FUJI PHOTO FILM CO., LTD. (JP) | 2004-12-07 | — | — | US | disclosed |
| US-6790809-B2 | HEAT-RESPONSIVE-DISCOLORING COLORING COMPOSITION EASILY DECOLORED BY DRY TREATMENT, AND WHICH DOES NOT RECOVER COLOR ONCE DISCOLORED, EVEN WHEN ITS TEMPERATURE IS LOWERED TO TEMPERATURE LOWER THAN DISCOLORATION INITIATION TEMPERATURE | FUJI PHOTO FILM CO., LTD. (JP) | 2004-09-14 | — | — | US | disclosed |
| US-6746830-B2 | CAPABLE OF RAPIDLY FORMING HIGH-QUALITY IMAGE EXCELLENT IN SHARPNESS, COLOR REPRODUCIBILITY AND OPTICAL READABILITY | FUJI PHOTO FILM CO., LTD. (JP) | 2004-06-08 | — | — | US | disclosed |
| US-20040006096-A1 | Substituted alkanohydroxamic acids and method of reducing TNFalpha levels | CELGENE CORPORATION | 2004-01-08 | — | — | US | disclosed |
| US-6656964-B2 | Reducing levels of tumor necrosis factor alpha; inhibition of undesireable levels of matrix metalloproteinases | CELGENE CORPORATION | 2003-12-02 | — | — | US | disclosed |
| US-20030186176-A1 | Silver halide photosensitive material and image-forming method using heat-responsive-discolorable coloring composition | FUJI PHOTO FILM CO., LTD. | 2003-10-02 | — | — | US | disclosed |
| US-20030064890-A1 | Heat-responsive-discoloring coloring composition, heat-responsive-discoloring coloring element comprising same and method for detecting thermal history of article | FUJI PHOTO FILM CO., LTD. | 2003-04-03 | — | — | US | disclosed |
| US-20020015903-A1 | Photosensitive material comprising reversibly decolorable colored layer and image-forming method using same | FUJI PHOTO FILM CO., LTD. | 2002-02-07 | — | — | US | disclosed |
| US-20010049371-A1 | Method of inhibiting phosphodiesterases with substituted alkanohydroxamic acids | CALGENE CORPORATION | 2001-12-06 | — | — | US | disclosed |
| US-6214857-B1 | REDUCES TUMOR NECROSIS FACTOR LEVELS | CELGENE CORPORATION | 2001-04-10 | — | — | US | disclosed |
| EP-0677564-B1 | Opaque/transparent thermochromic compositions and laminate | PILOT INK CO LTD (JP) | 1999-05-12 | — | — | EP | disclosed |
| EP-0827843-A1 | Temperature-dependent color/transparency storing resin composition and laminate member employing the same | THE PILOT INK CO., LTD. (JP) | 1998-03-11 | — | — | EP | disclosed |
| US-5721059-A | THERMOCHROMIC BLENDS COMPRISING AN ELECTRON-DONATING COLOR DYES, A PHENOLIC HYDROXY RADICAL AND A COMPOUND SELECTED FROM ALCOHOLS, ESTERS, KETONES AND CARBOXYLIC ACIDS IN VINYL ACETATE-VINYL CHLORIDE COPOLYMER; TOYS, COMPUTERS, OPTICS | THE PILOT INK CO., LTD. (JP) | 1998-02-24 | — | — | US | disclosed |
| US-5585425-A | Thermochromic opaque/transparent composition, laminate member employing the same, and three-dimensional member employing said laminate member and capable of concealing and revealing the interior | THE PILOT INK CO., LTD. (JP) | 1996-12-17 | — | — | US | disclosed |
| US-5490956-A | Thermochromic opaque composition, laminate member employing the same, and three-dimensional member employing said laminate member and capable of concealing and revealing the interior | PILOT INK CO., LTD. (JP) | 1996-02-13 | — | — | US | disclosed |
| EP-0677564-A2 | Opaque/transparent thermochromic compositions and laminate | THE PILOT INK CO., LTD. (JP) | 1995-10-18 | — | — | EP | disclosed |
| EP-0595577-A2 | Thermochromic opaque composition and uses thereof | THE PILOT INK CO., LTD. (JP) | 1994-05-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040006096-A1 | Substituted alkanohydroxamic acids and method of reducing TNFalpha levels | TNF, TNFRSF1A, LTA | DGKA 1648/4885DNM1 4187/4885PAM 930/4885 |
| US-20010049371-A1 | Method of inhibiting phosphodiesterases with substituted alkanohydroxamic acids | PDE3A, PDE2A, PDE3B | DGKA 1626/4885DNM1 3759/4885PAM 846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.