Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.50 |
| ▸ | TDO2 | P48775 | 2/20 | 0.49 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 2/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28138776 | 0.90 | FGFR4 (0.45) | PIK3CDPIK3CATDO2FGFR4USP2 | |
| SCHEMBL28138785 | 0.89 | PIK3CD (0.44) | PIK3CDPIK3CATDO2FGFR4USP2 | |
| SCHEMBL28139444 | 0.88 | FGFR4 (0.44) | PIK3CDPIK3CATDO2FGFR4USP2 | |
| SCHEMBL28018837 | 0.85 | LCK (0.50) | PIK3CDPIK3CATDO2FGFR4USP2 | |
| SCHEMBL28138760 | 0.85 | PIK3CA (0.50) | PIK3CDPIK3CATDO2FGFR4BACE1 | |
| SCHEMBL28138766 | 0.84 | TGFBR1 (0.40) | PIK3CDPIK3CATDO2FGFR4USP2 | |
| SCHEMBL18712121 | 0.84 | EGFR (0.54) | PIK3CDPIK3CATDO2FGFR4ALDH1A1 | |
| SCHEMBL15637895 | 0.83 | TGFBR1 (0.43) | PIK3CDPIK3CATDO2FGFR4USP2 | |
| SCHEMBL28873343 | 0.82 | TGFBR1 (0.48) | PIK3CDPIK3CATDO2FGFR4USP2 | |
| SCHEMBL18069431 | 0.82 | PIK3CA (0.52) | PIK3CDPIK3CATDO2FGFR4EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104837832-B | GDF-8 inhibitors | 里格尔药品股份有限公司 | 2019-04-26 | — | — | CN | claimed |
| CN-104837832-B | GDF-8 inhibitors | 里格尔药品股份有限公司 | 2019-04-26 | — | — | CN | disclosed |