Benzene

Benzene

SCHEMBL28296949

CC(C)(C)c1ccccc1Cl.c1ccccc1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 3/20 0.52
TSHR P16473 6/20 0.48
ALDH1A1 P00352 4/20 0.48
TDP1 Q9NUW8 3/20 0.48
LMNA P02545 2/20 0.45
CA2 P00918 2/20 0.44
HTR2A P28223 2/20 0.42
HTR2C P28335 2/20 0.42
OPRK1 P41145 2/20 0.42
KCNH2 Q12809 2/20 0.42
ADRA1A P35348 1/20 0.42
KCNA3 P22001 2/20 0.39
CYP2A6 P11509 1/20 0.39
HSD11B1 P28845 1/20 0.38
GABRA1 P14867 1/20 0.38
GABRB2 P47870 1/20 0.38
NPSR1 Q6W5P4 2/20 0.38
GLA P06280 2/20 0.38
RAB9A P51151 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL78489 0.97 TSHR (0.50) KCNN4TSHRALDH1A1TDP1LMNA
Chlorobenzene SCHEMBL28295200 0.93 TSHR (0.50) KCNN4TSHRALDH1A1TDP1LMNA
Formaldehyde SCHEMBL27601295 0.90 ALDH1A1 (0.44) KCNN4TSHRALDH1A1TDP1LMNA
SCHEMBL27635853 0.86 ALDH1A1 (0.41) KCNN4TSHRALDH1A1TDP1LMNA
SCHEMBL27759221 0.85 CYP2A6 (0.54) KCNN4TSHRALDH1A1TDP1LMNA
Formamide SCHEMBL28296947 0.84 KCNN4 (0.44) KCNN4TSHRALDH1A1TDP1LMNA
SCHEMBL7571745 0.81 KCNN4 (0.48) KCNN4TSHRALDH1A1TDP1LMNA
Formic Acid Methyl Ester SCHEMBL28296946 0.81 TDP1 (0.38) KCNN4TSHRALDH1A1TDP1LMNA
SCHEMBL6683582 0.79 KCNN4 (0.46) KCNN4TSHRALDH1A1TDP1LMNA
SCHEMBL6683028 0.79 KCNN4 (0.46) KCNN4TSHRALDH1A1TDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109694382-A A method of preparing aryl-boric acid ester at room temperature 广州医科大学 2019-04-30 CN disclosed