Formamide

Formamide

SCHEMBL28296947

CC(C)(C)c1ccccc1Cl.NC=O

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 1/20 0.44
ALDH1A1 P00352 4/20 0.40
TSHR P16473 3/20 0.40
TDP1 Q9NUW8 2/20 0.40
HSD11B1 P28845 3/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
CA2 P00918 1/20 0.37
LMNA P02545 1/20 0.36
L3MBTL1 Q9Y468 2/20 0.34
NPC1 O15118 1/20 0.34
GLA P06280 1/20 0.34
RAB9A P51151 1/20 0.34
ATM Q13315 1/20 0.34
KIF11 P52732 2/20 0.33
HTR2A P28223 1/20 0.33
HTR2C P28335 1/20 0.33
ADRA1A P35348 1/20 0.33
OPRK1 P41145 1/20 0.33
KCNH2 Q12809 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27635853 0.89 ALDH1A1 (0.41) KCNN4ALDH1A1TSHRTDP1HSD11B1
SCHEMBL78489 0.87 TSHR (0.50) KCNN4ALDH1A1TSHRTDP1HSD11B1
Formaldehyde SCHEMBL27601295 0.85 ALDH1A1 (0.44) KCNN4ALDH1A1TSHRTDP1HSD11B1
Benzene SCHEMBL28296949 0.84 KCNN4 (0.52) KCNN4ALDH1A1TSHRTDP1HSD11B1
Formic Acid Methyl Ester SCHEMBL28296946 0.84 TDP1 (0.38) KCNN4ALDH1A1TSHRTDP1HSD11B1
Chlorobenzene SCHEMBL28295200 0.78 TSHR (0.50) KCNN4ALDH1A1TSHRTDP1HSD11B1
SCHEMBL5276758 0.77 KCNN4 (0.41) KCNN4ALDH1A1TSHRTDP1HSD11B1
1,2-Dichlorobenzene SCHEMBL27496788 0.77 LMNA (0.62) ALDH1A1TSHRTDP1MEN1KMT2A
SCHEMBL31521320 0.73 KCNN4 (0.56) KCNN4ALDH1A1TSHRTDP1HSD11B1
SCHEMBL3669301 0.73 KCNN4 (0.56) KCNN4ALDH1A1TSHRTDP1HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109694382-A A method of preparing aryl-boric acid ester at room temperature 广州医科大学 2019-04-30 CN disclosed