Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.68 |
| ▸ | CYP1B1 | Q16678 | 6/20 | 0.68 |
| ▸ | MAOB | P27338 | 4/20 | 0.68 |
| ▸ | BCHE | P06276 | 3/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.68 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.68 |
| ▸ | ACHE | P22303 | 1/20 | 0.68 |
| ▸ | RECQL | P46063 | 1/20 | 0.68 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.68 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | RAB9A | P51151 | 3/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.65 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.65 |
| ▸ | RELA | Q04206 | 2/20 | 0.65 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.65 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28301215 | 0.86 | MAOB (0.62) | MAPTCYP1B1MAOBBCHELMNA | |
| SCHEMBL9915665 | 0.86 | CYP1B1 (0.91) | MAPTCYP1B1MAOBBCHELMNA | |
| SCHEMBL8431772 | 0.86 | CYP1B1 (0.91) | MAPTCYP1B1MAOBBCHELMNA | |
| SCHEMBL25232470 | 0.85 | MAPT (0.70) | MAPTCYP1B1MAOBBCHELMNA | |
| SCHEMBL27799120 | 0.85 | MAPT (0.70) | MAPTCYP1B1MAOBBCHELMNA | |
| SCHEMBL14681877 | 0.85 | MAPT (0.70) | MAPTCYP1B1MAOBBCHELMNA | |
| SCHEMBL28954817 | 0.83 | MAPT (0.68) | MAPTCYP1B1MAOBBCHELMNA | |
| SCHEMBL655661 | 0.83 | MAPT (0.68) | MAPTCYP1B1MAOBBCHELMNA | |
| SCHEMBL655660 | 0.83 | MAPT (0.68) | MAPTCYP1B1MAOBBCHELMNA | |
| Chalcone SCHEMBL27581 | 0.82 | CYP1B1 (1.00) | MAPTCYP1B1MAOBBCHELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109761842-A | The synthetic method of α-F- β-NHAc- carbonyls | 浙江工业大学 | 2019-05-17 | — | — | CN | disclosed |
| CN-109734571-A | The synthetic method of α-F- β-OH- carbonyls | 浙江工业大学 | 2019-05-10 | — | — | CN | disclosed |