1,4-Butanediol

1,4-Butanediol

SCHEMBL28296962

CCCC(C)(O)O.OCCCCO

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.50
ALDH1A1 P00352 4/20 0.48
LMNA P02545 2/20 0.48
HSD17B10 Q99714 1/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
TSHR P16473 1/20 0.48
CYP4F2 P78329 2/20 0.38
CYP4A11 Q02928 2/20 0.38
FDPS P14324 2/20 0.33
KDM4E B2RXH2 1/20 0.30
GGPS1 O95749 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL155401 0.85
SCHEMBL9630187 0.85
1,5-Pentanediol SCHEMBL21925315 0.84 LMNA (0.57) SMN1; SMN2ALDH1A1LMNAHSD17B10MEN1
1,6-Hexanediol SCHEMBL6261489 0.84 LMNA (0.57) SMN1; SMN2ALDH1A1LMNAHSD17B10MEN1
SCHEMBL5179658 0.82
1-Hexanol SCHEMBL3689164 0.82 LMNA (0.62) SMN1; SMN2ALDH1A1LMNAHSD17B10MEN1
SCHEMBL5907177 0.81 SMN1; SMN2 (0.48) SMN1; SMN2ALDH1A1LMNAHSD17B10MEN1
SCHEMBL28299841 0.80 ALDH1A1 (0.33) SMN1; SMN2ALDH1A1LMNAHSD17B10MEN1
SCHEMBL27953330 0.80 CYP4F2 (0.43) SMN1; SMN2ALDH1A1LMNAHSD17B10MEN1
SCHEMBL28101093 0.80 CYP4F2 (0.43) SMN1; SMN2ALDH1A1LMNAHSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109734556-A A kind of preparation method of 1,4 butanediol composition 内蒙古东景生物环保科技有限公司 2019-05-10 CN disclosed