Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LGMN | Q99538 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19972301 | 0.81 | ALDH1A1 (0.36) | ALDH1A1MAPTHTTPSEN1PSEN2 | |
| SCHEMBL12525150 | 0.72 | MAPT (0.46) | ALDH1A1MAPTHTTCES2CES1 | |
| SCHEMBL19972227 | 0.70 | KMT2A (0.38) | ALDH1A1MAPT | |
| SCHEMBL756201 | 0.69 | HTT (0.32) | ALDH1A1MAPTHTT | |
| SCHEMBL9997229 | 0.69 | CES2 (0.42) | ALDH1A1MAPTPSEN1PSEN2APH1B | |
| SCHEMBL31117167 | 0.68 | CES2 (0.46) | ALDH1A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL31560789 | 0.68 | CES2 (0.46) | ALDH1A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL19985861 | 0.67 | KMT2A (0.38) | ALDH1A1MAPT | |
| SCHEMBL4533837 | 0.67 | CES2 (0.45) | ALDH1A1MAPTHTTPSEN1PSEN2 | |
| SCHEMBL15499253 | 0.67 | ALDH1A1 (0.36) | ALDH1A1MAPTHTTPSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715614-A | The 6 yuan of cyclammonium or lactams replaced with urea and phenyl | 格吕伦塔尔有限公司 | 2019-05-03 | — | — | CN | disclosed |