Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.50 |
| ▸ | TTK | P33981 | 1/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.45 |
| ▸ | JUN | P05412 | 2/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ADK | P55263 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | CCNC | P24863 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28298603 | 0.86 | MET (0.48) | KDM4EMAPTL3MBTL1NPC1RAB9A | |
| SCHEMBL28070394 | 0.83 | TTK (0.52) | CNR2TTKMAPK10JUNMAPK8 | |
| SCHEMBL28876921 | 0.79 | HTR2A (0.43) | KDM4EMAPTL3MBTL1NPC1GAA | |
| SCHEMBL29248284 | 0.75 | TNF (0.47) | MAPK10KDM4EPIK3CA | |
| SCHEMBL12970479 | 0.74 | ADORA2A (0.43) | MAPK10KDM4EMAPTNPC1GAA | |
| SCHEMBL31038714 | 0.73 | EGFR (0.44) | MAPK10KDM4EMAPK1PIK3CA | |
| SCHEMBL3074807 | 0.73 | EGFR (0.50) | MAPK10KDM4EMAPTGAASMN1; SMN2 | |
| SCHEMBL16513631 | 0.72 | MAPK10 (0.79) | TTKMAPK10JUNMAPK8 | |
| SCHEMBL29847439 | 0.72 | MAPK10 (0.79) | TTKMAPK10JUNMAPK8 | |
| SCHEMBL2368945 | 0.71 | MAPT (0.53) | CNR2MAPK10KDM4EMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109851617-A | Chemical entities, composition and method | 润新生物公司 | 2019-06-07 | — | — | CN | disclosed |