Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 1/20 | 0.52 |
| ▸ | DHFR | P00374 | 2/20 | 0.51 |
| ▸ | JUN | P05412 | 3/20 | 0.49 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.49 |
| ▸ | CNR2 | P34972 | 2/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | ADK | P55263 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 4/20 | 0.46 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | KIT | P10721 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28070389 | 0.86 | HRH4 (0.52) | DHFRFYNLCKSRCKDR | |
| SCHEMBL28297006 | 0.83 | CNR2 (0.50) | TTKDHFRJUNMAPK8MAPK10 | |
| SCHEMBL2558872 | 0.80 | DHFR (0.60) | DHFRPIK3CAFYNADKMTOR | |
| SCHEMBL16513631 | 0.76 | MAPK10 (0.79) | TTKJUNMAPK8MAPK10CDK1 | |
| SCHEMBL29847439 | 0.76 | MAPK10 (0.79) | TTKJUNMAPK8MAPK10CDK1 | |
| SCHEMBL30634004 | 0.76 | ADORA1 (0.49) | DHFRLCKKDR | |
| SCHEMBL15228702 | 0.75 | LCK (0.41) | DHFRLCKSRCKDRMAPT | |
| SCHEMBL16514799 | 0.75 | JAK2 (0.66) | TTKJUNMAPK8MAPK10CDK1 | |
| SCHEMBL31114713 | 0.74 | SMN1; SMN2 (0.55) | CNR2PIK3CAFYNADKPIK3CG | |
| SCHEMBL28120724 | 0.74 | DHFR (0.52) | DHFRLCKSRCKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105682661-A | Certain chemical entities, compositions, and methods | 润新生物公司 | 2016-06-15 | — | — | CN | disclosed |