SCHEMBL28297022

SCHEMBL28297022

OB(O)Oc1ccc2oc3ccccc3c2c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.55
MAPT P10636 5/20 0.54
NPC1 O15118 4/20 0.54
ALDH1A1 P00352 4/20 0.49
RAB9A P51151 3/20 0.49
HPGD P15428 3/20 0.49
KDM4E B2RXH2 2/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
MAOA P21397 3/20 0.47
POLB P06746 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
AHR P35869 2/20 0.44
PTGER4 P35408 1/20 0.44
NPSR1 Q6W5P4 1/20 0.41
RXFP1 Q9HBX9 1/20 0.41
ACSL1 P33121 2/20 0.41
ACSL6 Q9UKU0 2/20 0.41
CYP1A2 P05177 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28708694 0.90 NPC1 (0.51) LMNAMAPTNPC1ALDH1A1RAB9A
SCHEMBL31373207 0.87 LMNA (0.42) LMNAMAPTNPC1ALDH1A1RAB9A
SCHEMBL31373206 0.83 ABCG2 (0.41) LMNAMAPTNPC1ALDH1A1RAB9A
SCHEMBL30378873 0.83 PIM1 (0.44) LMNAMAPTNPC1ALDH1A1RAB9A
SCHEMBL30575168 0.77 MAPT (0.35) LMNAMAPTALDH1A1HPGDKDM4E
SCHEMBL28099661 0.77 MAPT (0.35) LMNAMAPTALDH1A1HPGDKDM4E
SCHEMBL30463426 0.77 MAPT (0.35) LMNAMAPTALDH1A1HPGDKDM4E
SCHEMBL5848964 0.77 MAOA (0.75) LMNAMAPTNPC1ALDH1A1RAB9A
SCHEMBL30137602 0.77 MAOA (0.75) LMNAMAPTNPC1ALDH1A1RAB9A
SCHEMBL30166452 0.76 LMNA (0.35) LMNAMAPTNPC1ALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117412942-A Organic compound and application thereof 浙江光昊光电科技有限公司 2024-01-16 CN disclosed
CN-117279912-A Compound, material for organic electroluminescent element, and electronic device 出光兴产株式会社 2023-12-22 CN disclosed
CN-111164079-B Compound for organic electric element, organic electric element using same, and electronic device using same 德山新勒克斯有限公司 2023-07-25 CN disclosed
CN-116120192-A Compound for organic electric element, organic electric element using same, and electronic device using same 德山新勒克斯有限公司 2023-05-16 CN disclosed
CN-107759527-B Compound, application thereof and organic electroluminescent device 北京鼎材科技有限公司 2022-03-04 CN disclosed
CN-109810120-B Carbazole-thienopyrazine derivative, preparation method, application and device thereof 武汉尚赛光电科技有限公司 2020-10-30 CN disclosed
CN-109810120-A A kind of derivative of carbazole-thienopyrazine and preparation method thereof, application and device 武汉尚赛光电科技有限公司 2019-05-28 CN disclosed