Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14686714 | 0.81 | MEN1 (0.37) | KMT2ASMN1; SMN2 | |
| SCHEMBL738878 | 0.81 | MEN1 (0.37) | KMT2ASMN1; SMN2 | |
| SCHEMBL28325760 | 0.77 | DDB1 (0.42) | TDP1KDM1AKDM4EALDH1A1HPGD | |
| SCHEMBL23617441 | 0.71 | KCNH2 (0.36) | KCNH2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5187861 | 0.70 | MEN1 (0.36) | KMT2ASMN1; SMN2 | |
| SCHEMBL10153581 | 0.67 | CHRNB2 (0.45) | KCNH2TDP1KDM1AATMCA1 | |
| SCHEMBL12572359 | 0.64 | GSK3B (0.50) | TDP1KDM1AKMT2ASMN1; SMN2CA1 | |
| SCHEMBL21536565 | 0.64 | GSK3B (0.50) | TDP1KDM1AKMT2ASMN1; SMN2CA1 | |
| SCHEMBL22039449 | 0.64 | TDP1 (0.46) | KCNH2TDP1KMT2A | |
| SCHEMBL7237762 | 0.64 | TDP1 (0.46) | KCNH2TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106866574-B | A kind of method of reduction amination synthesis of chiral sulfanilamide (SN) in palladium chtalyst asymmetric molecult | 中国科学院大连化学物理研究所 | 2019-06-04 | — | — | CN | disclosed |