Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.34 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.34 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23617235 | 0.84 | SRD5A1 (0.41) | — | |
| SCHEMBL3652840 | 0.84 | CHRNB2 (0.39) | — | |
| SCHEMBL23617234 | 0.74 | DRD2 (0.47) | HTR2AHTR2CKDM4EALDH1A1HSD17B10 | |
| SCHEMBL22022123 | 0.73 | HRH3 (0.43) | KCNH2HTR2AHTR2CKDM4EALDH1A1 | |
| SCHEMBL23617571 | 0.72 | DDB1 (0.40) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL28297380 | 0.71 | KCNH2 (0.37) | KCNH2ATMKDM4EALDH1A1HPGD | |
| SCHEMBL23617463 | 0.71 | ALDH1A1 (0.38) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL23617414 | 0.70 | HCAR2 (0.34) | GAA | |
| SCHEMBL23617454 | 0.69 | — | — | |
| SCHEMBL23617255 | 0.69 | MAPT (0.35) | KDM4EALDH1A1HPGDGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3589630-B1 | CYCLIC SULFAMIDE COMPOUNDS AND METHODS OF USING SAME | ASSEMBLY BIOSCIENCES INC (US) | 2021-07-07 | — | — | EP | disclosed |