Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1480776 | 0.79 | GABRA1 (0.42) | — | |
| SCHEMBL1026876 | 0.76 | CES2 (0.39) | PDE2A | |
| SCHEMBL15872940 | 0.75 | — | — | |
| SCHEMBL5184322 | 0.74 | PDE2A (0.42) | PDE2A | |
| SCHEMBL1237730 | 0.74 | PDE2A (0.39) | PDE2A | |
| SCHEMBL1663650 | 0.73 | PDE2A (0.36) | PDE2A | |
| SCHEMBL9383335 | 0.72 | PDE2A (0.33) | PDE2A | |
| Hydrochloric Acid SCHEMBL3162563 | 0.72 | PDE2A (0.38) | PDE2A | |
| SCHEMBL5705765 | 0.70 | IDO1 (0.44) | PDE2A | |
| SCHEMBL5804696 | 0.69 | TSHR (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105980361-B | For treating the 5- benzylisoquinoline derivative of cardiovascular disease | 法国施维雅药厂 | 2019-05-21 | — | — | CN | claimed |
| CN-105980361-B | For treating the 5- benzylisoquinoline derivative of cardiovascular disease | 法国施维雅药厂 | 2019-05-21 | — | — | CN | disclosed |