Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 6/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | CD38 | P28907 | 3/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.36 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28298922 | 0.95 | MEN1 (0.38) | MEN1KMT2AKDM4EPARP1CYP3A4 | |
| SCHEMBL28232396 | 0.89 | KDM4E (0.40) | MEN1KMT2AKDM4EPARP1CYP3A4 | |
| SCHEMBL6013407 | 0.86 | BID (0.48) | MEN1KMT2AKDM4ECYP3A4NR1I2 | |
| SCHEMBL7517986 | 0.84 | BID (0.50) | MEN1KMT2AKDM4ECYP3A4NR1I2 | |
| SCHEMBL6013409 | 0.84 | BID (0.50) | MEN1KMT2AKDM4ECYP3A4NR1I2 | |
| SCHEMBL486383 | 0.84 | MEN1 (0.45) | MEN1KMT2AKDM4EPARP1CYP3A4 | |
| SCHEMBL30514834 | 0.84 | PARP1 (0.38) | MEN1KMT2AKDM4EPARP1CYP3A4 | |
| SCHEMBL28182515 | 0.84 | PARP1 (0.38) | MEN1KMT2AKDM4EPARP1CYP3A4 | |
| SCHEMBL29009406 | 0.83 | MAPT (0.42) | MEN1KMT2AKDM4EPARP1CYP3A4 | |
| Hydrochloric Acid SCHEMBL7557316 | 0.83 | BID (0.49) | MEN1KMT2AKDM4ECYP3A4NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109863146-A | Aryl-linking compound as immunomodulator | 百时美施贵宝公司 | 2019-06-07 | — | — | CN | disclosed |