Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | RAD51 | Q06609 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29563706 | 0.88 | ALDH1A1 (0.56) | ALDH1A1MAPTKDM4EKMT2ARAD51 | |
| SCHEMBL18658495 | 0.88 | ALDH1A1 (0.56) | ALDH1A1MAPTKDM4EKMT2ARAD51 | |
| SCHEMBL3983141 | 0.86 | ALDH1A1 (0.60) | ALDH1A1MAPTKDM4EKMT2ARAD51 | |
| SCHEMBL31704313 | 0.82 | ALDH1A1 (0.56) | ALDH1A1MAPTKDM4EKMT2ARAD51 | |
| SCHEMBL28282044 | 0.82 | RAD51 (0.57) | ALDH1A1MAPTKDM4EKMT2ARAD51 | |
| SCHEMBL19784834 | 0.82 | ALDH1A1 (0.59) | ALDH1A1MAPTKDM4EKMT2ARAD51 | |
| SCHEMBL17868230 | 0.82 | POLB (0.67) | ALDH1A1MAPTKDM4EKMT2ARAD51 | |
| SCHEMBL23106722 | 0.81 | ALDH1A1 (0.55) | ALDH1A1MAPTKDM4EKMT2ARAD51 | |
| SCHEMBL30022824 | 0.81 | ALDH1A1 (0.55) | ALDH1A1MAPTKDM4EKMT2ARAD51 | |
| SCHEMBL4357633 | 0.80 | KMT2A (0.59) | ALDH1A1MAPTKDM4EKMT2ARAD51 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109843892-B | Oxadiazepinone derivatives and their use in the treatment of hepatitis B infections | 诺维拉治疗公司 | 2022-01-25 | — | — | CN | disclosed |
| CN-109843892-A | Dislike diazepine ketone derivatives and its purposes in treatment hepatitis B infection | 诺维拉治疗公司 | 2019-06-04 | — | — | CN | disclosed |