Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | RAD51 | Q06609 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | FAAH | O00519 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | BRD4 | O60885 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28282044 | 0.86 | RAD51 (0.57) | ALDH1A1MAPTKDM4ENPC1RAB9A | |
| SCHEMBL29563706 | 0.86 | ALDH1A1 (0.56) | ALDH1A1MAPTKDM4ENPC1RAB9A | |
| SCHEMBL28297902 | 0.86 | ALDH1A1 (0.56) | ALDH1A1MAPTKDM4ENPC1RAB9A | |
| SCHEMBL19784834 | 0.86 | ALDH1A1 (0.59) | ALDH1A1MAPTKDM4ENPC1RAB9A | |
| SCHEMBL2488923 | 0.86 | POLB (0.63) | ALDH1A1MAPTKDM4ENPC1RAB9A | |
| SCHEMBL29444257 | 0.86 | POLB (0.63) | ALDH1A1MAPTKDM4ENPC1RAB9A | |
| SCHEMBL17868230 | 0.86 | POLB (0.67) | ALDH1A1MAPTKDM4ENPC1RAB9A | |
| SCHEMBL18658495 | 0.86 | ALDH1A1 (0.56) | ALDH1A1MAPTKDM4ENPC1RAB9A | |
| SCHEMBL29739620 | 0.86 | ALDH1A1 (0.59) | ALDH1A1MAPTKDM4ENPC1RAB9A | |
| SCHEMBL17925573 | 0.85 | ALDH1A1 (0.57) | ALDH1A1MAPTKDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12624004-B2 | Opioid receptor agonist, preparation method therefor and pharmaceutical use thereof | FUDAN UNIVERSITY (CN) | 2026-05-12 | — | — | US | disclosed |
| US-11572372-B2 | Anti-HBVtetrahydroisoxazolo[4,3-c]pyridine compounds | MEDSHINE DISCOVERY INC. (CN) | 2023-02-07 | — | — | US | disclosed |
| US-20230027752-A1 | OPIOID RECEPTOR AGONIST, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | FUDAN UNIVERSITY (CN) | 2023-01-26 | — | — | US | disclosed |
| US-20230027752-A1 | OPIOID RECEPTOR AGONIST, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | FUDAN UNIVERSITY (CN) | 2023-01-26 | — | — | US | disclosed |
| CN-112759545-B | 3- (dimethylamino methyl) piperidine-4-alcohol derivative and preparation method and pharmaceutical application thereof | 复旦大学 | 2022-12-13 | — | — | CN | disclosed |
| CN-112759545-A | 3- (dimethylamino methyl) piperidine-4-alcohol derivative and preparation method and pharmaceutical application thereof | 复旦大学 | 2021-05-07 | — | — | CN | disclosed |
| US-20200377517-A1 | ANTI-HBVTETRAHYDROISOXAZOLO[4,3-C]PYRIDINE COMPOUNDS | MEDSHINE DISCOVERY INC. (CN) | 2020-12-03 | — | — | US | disclosed |
| EP-3712139-A1 | ANTI-HBV TETRAHYDROISOXAZOLO[4,3-C]PYRIDINE COMPOUNDS | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2020-09-23 | — | — | EP | disclosed |
| EP-1380574-B1 | 9-aminoacridine derivates and process for the preparation thereof | SAMJIN PHARM CO LTD (KR) | 2009-05-20 | — | — | EP | disclosed |
| EP-1380574-A1 | 9-aminoacridine derivates and process for the preparation thereof | Samjin Pharmaceutical Co., Ltd. (KR) | 2004-01-14 | — | — | EP | disclosed |
| US-6620936-B2 | Antitumor agents, topoisomerase inhibitors, notoxic | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2003-09-16 | — | — | US | disclosed |
| US-20020111491-A1 | 9-aminoacridine derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2002-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12624004-B2 | Opioid receptor agonist, preparation method therefor and pharmaceutical use thereof | OPRM1, OPRD1, OPRK1 | ALDH1A1 1377/4885MAPT 2706/4885KDM4E 1096/4885 |
| US-20230027752-A1 | OPIOID RECEPTOR AGONIST, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | OPRM1, OPRD1, OPRL1 | ALDH1A1 1025/4885MAPT 2057/4885KDM4E 2284/4885 |
| US-11572372-B2 | Anti-HBVtetrahydroisoxazolo[4,3-c]pyridine compounds | HAVCR2, HCCS, CD4 | ALDH1A1 3483/4885MAPT 3654/4885KDM4E 1857/4885 |
| US-20020111491-A1 | 9-aminoacridine derivatives and process for the preparation thereof | ALKBH1, ADCY9, CCR9 | ALDH1A1 97/4885MAPT 4812/4885KDM4E 1567/4885 |
| US-20200377517-A1 | ANTI-HBVTETRAHYDROISOXAZOLO[4,3-C]PYRIDINE COMPOUNDS | HAVCR2, HCCS, CD4 | ALDH1A1 3483/4885MAPT 3654/4885KDM4E 1857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.