Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 3/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.38 |
| ▸ | NT5E | P21589 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19642149 | 0.88 | PDE4A (0.39) | CACNA1HNR3C2NT5EKDM4EALDH1A1 | |
| SCHEMBL30187402 | 0.88 | PDE4A (0.39) | CACNA1HNR3C2NT5EKDM4EALDH1A1 | |
| SCHEMBL28299533 | 0.87 | KDM4E (0.41) | CACNA1HNR3C2NT5EKDM4EALDH1A1 | |
| SCHEMBL28299380 | 0.84 | MEN1 (0.49) | CACNA1HNR3C2NT5EKDM4EALDH1A1 | |
| SCHEMBL28873447 | 0.84 | KDM4E (0.51) | CACNA1HNR3C2KDM4EALDH1A1PDE4A | |
| SCHEMBL19659889 | 0.84 | PDE4A (0.51) | CACNA1HNR3C2KDM4EALDH1A1PDE4A | |
| SCHEMBL28297923 | 0.82 | MEN1 (0.41) | CACNA1HNR3C2KDM4EPDE4APDE4B | |
| SCHEMBL28299379 | 0.78 | MAOB (0.41) | KDM4EALDH1A1MAOBMAOAPTGS2 | |
| SCHEMBL28297928 | 0.77 | NT5E (0.35) | CACNA1HNR3C2NT5EKDM4EALDH1A1 | |
| SCHEMBL30187450 | 0.76 | KDM4E (0.41) | CACNA1HKDM4EALDH1A1PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109863140-A | 3- oxo -2,6- diphenyl -2,3- dihydrogen dazin -4- formamide | 拜耳医药股份有限公司 | 2019-06-07 | — | — | CN | disclosed |