Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30187450 | 0.89 | KDM4E (0.41) | KDM4EACSS2PDE4APDE4BPDE4C | |
| SCHEMBL19642572 | 0.89 | KDM4E (0.41) | KDM4EACSS2PDE4APDE4BPDE4C | |
| SCHEMBL28873447 | 0.88 | KDM4E (0.51) | KDM4EPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL28297925 | 0.87 | CACNA1H (0.39) | KDM4EPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL28297923 | 0.86 | MEN1 (0.41) | KDM4EPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL19660389 | 0.85 | PDE4A (0.51) | KDM4EACSS2PDE4APDE4BPDE4C | |
| SCHEMBL28299380 | 0.82 | MEN1 (0.49) | KDM4EPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL19642610 | 0.79 | KDM4E (0.48) | KDM4EPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL30187464 | 0.79 | KDM4E (0.48) | KDM4EPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL28297921 | 0.78 | PDE4A (0.46) | PDE4APDE4BPDE4CPDE4DMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109863140-A | 3- oxo -2,6- diphenyl -2,3- dihydrogen dazin -4- formamide | 拜耳医药股份有限公司 | 2019-06-07 | — | — | CN | disclosed |