Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SLC5A1 | P13866 | 4/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.39 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30187456 | 0.89 | MEN1 (0.41) | MEN1KMT2ASMN1; SMN2KDM4ESLC5A1 | |
| SCHEMBL19643410 | 0.89 | MEN1 (0.41) | MEN1KMT2ASMN1; SMN2KDM4ESLC5A1 | |
| SCHEMBL28873447 | 0.88 | KDM4E (0.51) | MEN1KMT2AKDM4EPDE4APDE4B | |
| SCHEMBL28299533 | 0.86 | KDM4E (0.41) | MEN1KMT2AKDM4EPDE4APDE4B | |
| SCHEMBL19660003 | 0.85 | PDE4A (0.51) | MEN1KMT2ASMN1; SMN2KDM4ESLC5A1 | |
| SCHEMBL28297925 | 0.82 | CACNA1H (0.39) | MEN1KMT2AKDM4EPDE4APDE4B | |
| SCHEMBL28299380 | 0.82 | MEN1 (0.49) | MEN1KMT2ASMN1; SMN2KDM4EPDE4A | |
| SCHEMBL19642610 | 0.79 | KDM4E (0.48) | MEN1KMT2AKDM4EPDE4APDE4B | |
| SCHEMBL30187464 | 0.79 | KDM4E (0.48) | MEN1KMT2AKDM4EPDE4APDE4B | |
| SCHEMBL28297926 | 0.78 | PDE4A (0.46) | MEN1KMT2ASMN1; SMN2SLC5A1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109863140-A | 3- oxo -2,6- diphenyl -2,3- dihydrogen dazin -4- formamide | 拜耳医药股份有限公司 | 2019-06-07 | — | — | CN | disclosed |