SCHEMBL28298033

SCHEMBL28298033

Oc1cc(OCc2ccccc2)ccc1-c1ccc(Cl)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 5/20 0.56
MAPT P10636 4/20 0.56
MAOB P27338 4/20 0.56
MAPK1 P28482 2/20 0.56
KDM4E B2RXH2 1/20 0.56
HSP90AA1 P07900 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
GSTP1 P09211 2/20 0.56
NOD2 Q9HC29 1/20 0.54
LMNA P02545 2/20 0.53
CYP1A2 P05177 1/20 0.53
PTGS1 P23219 1/20 0.53
SLC6A2 P23975 1/20 0.53
CYP2C19 P33261 1/20 0.53
PTGS2 P35354 1/20 0.53
SLC6A3 Q01959 1/20 0.53
HIF1A Q16665 1/20 0.53
HDAC6 Q9UBN7 1/20 0.53
MAOA P21397 1/20 0.52
KCNA3 P22001 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7691338 0.82 GSTP1 (0.54) NPSR1MAPTMAOBGSTP1PTGS1
SCHEMBL197223 0.80 LMNA (0.67) MAPTMAOBLMNACYP1A2PTGS1
SCHEMBL19319763 0.80 NPSR1 (0.53) NPSR1MAPTMAOBMAPK1KDM4E
SCHEMBL28298032 0.80 GSTP1 (0.51) NPSR1MAPTMAOBGSTP1CYP1A2
SCHEMBL30629210 0.79 GSTP1 (0.57) MAPTMAOBGSTP1LMNACYP1A2
SCHEMBL32675258 0.79 LMNA (0.61) MAPTMAOBLMNACYP1A2PTGS1
SCHEMBL574143 0.79 LMNA (0.61) MAPTMAOBLMNACYP1A2PTGS1
SCHEMBL19319765 0.79 NPSR1 (0.52) NPSR1MAPTMAOBMAPK1KDM4E
SCHEMBL1532839 0.78 LMNA (0.59) MAOBLMNACYP1A2PTGS1SLC6A2
SCHEMBL8668267 0.77 LMNA (0.59) NPSR1MAPTMAOBMAPK1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107083052-B Polyamide material and preparation method thereof for welding assembly 深圳市前海宇昕科技有限公司 2019-05-03 CN disclosed