SCHEMBL197223

SCHEMBL197223

Clc1ccc(OCc2ccccc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.67
CYP1A2 P05177 1/20 0.67
PTGS1 P23219 1/20 0.67
SLC6A2 P23975 1/20 0.67
CYP2C19 P33261 1/20 0.67
PTGS2 P35354 1/20 0.67
SLC6A3 Q01959 1/20 0.67
HIF1A Q16665 1/20 0.67
HDAC6 Q9UBN7 1/20 0.67
BCHE P06276 2/20 0.66
MAOB P27338 7/20 0.66
APP P05067 1/20 0.66
GAA P10253 1/20 0.64
MAPT P10636 1/20 0.64
MAOA P21397 1/20 0.64
RAB9A P51151 1/20 0.64
SMN1; SMN2 Q16637 1/20 0.64
L3MBTL1 Q9Y468 1/20 0.64
NR4A2 P43354 2/20 0.62
AR P10275 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11846870 0.92 BCHE (0.63) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL5441069 0.91 MAOB (0.66) LMNACYP1A2PTGS1SLC6A2CYP2C19
Acetonitrile SCHEMBL10710304 0.89 MAOB (0.64) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL10991891 0.89 MAOB (0.80) LMNABCHEMAOBAPPMAOA
SCHEMBL339813 0.89 LMNA (0.82) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL27367676 0.89 LMNA (0.82) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL11857425 0.88 MAOB (0.62) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL8503299 0.86 SRD5A2 (0.77) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL197713 0.86 BCHE (0.53) LMNACYP1A2PTGS1SLC6A2CYP2C19
SCHEMBL3774293 0.85 MRGPRX4 (0.68) MAOBAPPMAOARAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102351675-A Preparation process of 4-chlorophenyl benzyl ketone UNIV CHANGZHOU 2012-02-15 CN claimed
US-20090023075-A1 Nonaqueous electrolyte including Diphenyl ether and lithium secondary battery using thereof PANAX ETEC CO., LTD (KR) 2009-01-22 US claimed
EP-1979978-A1 NONAQUEOUS ELECTROLYTE INCLUDING DIPHENYL ETHER AND LITHIUM SECONDARY BATTERY USING THEREOF Cheil Industries Inc. (KR) 2008-10-15 EP claimed
WO-2007081151-A1 NONAQUEOUS ELECTROLYTE INCLUDING DIPHENYL ETHER AND LITHIUM SECONDARY BATTERY USING THEREOF CHEIL INDUSTRIES INC. (KR) 2007-07-19 WO claimed
WO-2005012227-A2 PROCESS FOR PREPARATION OF 2-(3-DIISOPROPYLAMINO-1-PHENYLPROPYL)-4-HYDROXYMETHYL-PHENOL, A METABOLITE OF TOLTERODINE RANBAXY LABORATORIES LIMITED (IN) 2005-02-10 WO claimed
US-5072017-A Condensation of para-substituted phenol with benzylating agent in presence of faujasite type zeolite; antioxidants, bactericides BAYER AKTIENGESELLSCHAFT (DE) 1991-12-10 US claimed
US-11919056-B2 Environmentally friendly excreta removal material MODI KAPIL (IN) 2024-03-05 US disclosed
WO-2024010810-A2 FC CONJUGATES INCLUDING AN INHIBITOR OF CD73 AND USES THEREOF CIDARA THERAPEUTICS, INC. (US) 2024-01-11 WO disclosed
CN-115677480-A TiO for preparing acid by selectively oxidizing primary alcohol under mild condition 2 Method for NaBr photocatalysis system 东南大学 2023-02-03 CN disclosed
CN-112574010-B Preparation method of triphenylene derivative 上海康鹏科技股份有限公司 2022-11-29 CN disclosed
US-20220127266-A1 MALIC ENZYME INHIBITORS SUN PHARMA ADVANCED RESEARCH COMPANY LTD (IN) 2022-04-28 US disclosed
US-11225480-B2 Malic enzyme inhibitors SUN PHARMA ADVANCED RESEARCH COMPANY LTD (IN) 2022-01-18 US disclosed
US-20210346925-A1 ENVIRONMENTALLY FRIENDLY EXCRETA REMOVAL MATERIAL MODI KAPIL (IN) 2021-11-11 US disclosed
EP-0278211-A1 Process for the manufacture of p-substituted o-benzylphenols BAYER AG (DE) 1988-08-17 EP disclosed
EP-0220965-A2 Resinous composition capable of releasing a bioactive substance at a controlled rate Nippon Paint Co., Ltd. (JP) 1987-05-06 EP disclosed
EP-0009787-B2 PROCESS FOR THE MONOHALOGENATION OF ALKYLBENZENES IN ALPHA POSITION BAYER AG (DE) 1986-07-09 EP disclosed
US-4401821-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1983-08-30 US disclosed
EP-0044536-A1 Plant growth regulators and their use J.T. Baker Chemical Co. (US) 1982-01-27 EP disclosed
EP-0009787-B1 PROCESS FOR THE MONOHALOGENATION OF ALKYLBENZENES IN ALPHA POSITION BAYER AG (DE) 1982-01-13 EP disclosed
US-4267280-A Controlled release pesticides and method of preparation HOPKINS, MADISON WISCONSIN A CORP OF WISCONSIN 1981-05-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11225480-B2 Malic enzyme inhibitors ME1, RNASE1, ME2 LMNA 3853/4885CYP1A2 1493/4885PTGS1 2223/4885
US-20220127266-A1 MALIC ENZYME INHIBITORS ME1, ME2, ME3 LMNA 4129/4885CYP1A2 2229/4885PTGS1 1749/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.