Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 2/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.40 |
| ▸ | EGLN2 | Q96KS0 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.33 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.31 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.31 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10758728 | 0.78 | GABRG2 (0.36) | GABRG2GABRB3GABRA5EGLN2NPC1 | |
| SCHEMBL20684766 | 0.74 | GABRG2 (0.34) | GABRG2GABRB3GABRA5EGLN2MAPK14 | |
| SCHEMBL21849283 | 0.71 | CYP1A2 (0.41) | NPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL15771331 | 0.70 | ATR (0.32) | — | |
| SCHEMBL15769939 | 0.70 | — | — | |
| SCHEMBL1040579 | 0.70 | GABRG2 (0.36) | GABRG2GABRB3GABRA5EGLN2 | |
| SCHEMBL10166462 | 0.69 | MAPK1 (0.41) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22052993 | 0.69 | KCNH2 (0.40) | EGLN2NPC1RAB9ASMN1; SMN2PDE4B | |
| SCHEMBL12693213 | 0.69 | NPC1 (0.46) | GABRG2GABRB3GABRA5NPC1RAB9A | |
| SCHEMBL25078673 | 0.68 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107406450-B | Method for preparing high-purity sulfonamide compound and intermediate thereof | 泸州东方农化有限公司 | 2019-06-04 | — | — | CN | disclosed |
| CN-107406450-A | Method for preparing high-purity sulfonamide compound and intermediate thereof | 泸州东方农化有限公司 | 2017-11-28 | — | — | CN | disclosed |