Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27566300 | 0.91 | HPGD (0.36) | HPGDRECQLSMN1; SMN2HRH3CHRM2 | |
| SCHEMBL27950765 | 0.84 | HPGD (0.34) | HPGDRECQLSMN1; SMN2HRH3LMNA | |
| SCHEMBL27935423 | 0.84 | HPGD (0.34) | HPGDRECQLSMN1; SMN2HRH3LMNA | |
| SCHEMBL27751949 | 0.83 | HPGD (0.34) | HPGDRECQLSMN1; SMN2HRH3CHRM2 | |
| SCHEMBL28125892 | 0.83 | SMN1; SMN2 (0.41) | HPGDSMN1; SMN2CHRM1LMNA | |
| SCHEMBL27643661 | 0.80 | HPGD (0.36) | HPGDRECQLSMN1; SMN2HRH3LMNA | |
| SCHEMBL27836128 | 0.80 | HPGD (0.32) | HPGDRECQLSMN1; SMN2HRH3 | |
| SCHEMBL28878334 | 0.79 | HPGD (0.54) | HPGDRECQLSMN1; SMN2LMNA | |
| SCHEMBL27915375 | 0.79 | SMN1; SMN2 (0.47) | HPGDSMN1; SMN2CHRM1 | |
| SCHEMBL28064466 | 0.77 | SMN1; SMN2 (0.54) | HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109790143-A | Amine-linked C for target protein degradation3-glutarimide solution stator body | C4医药公司 | 2019-05-21 | — | — | CN | disclosed |