Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | PREP | P48147 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28310203 | 0.89 | HPGD (0.63) | HPGDSMN1; SMN2RECQLALDH1A1PREP | |
| SCHEMBL2146346 | 0.83 | HPGD (0.49) | HPGDSMN1; SMN2ALDH1A1TSHRLMNA | |
| SCHEMBL27950765 | 0.80 | HPGD (0.34) | HPGDSMN1; SMN2RECQLALDH1A1HSD17B10 | |
| SCHEMBL27935423 | 0.80 | HPGD (0.34) | HPGDSMN1; SMN2RECQLALDH1A1HSD17B10 | |
| SCHEMBL27838575 | 0.80 | HPGD (0.47) | HPGDSMN1; SMN2RECQLALDH1A1HTT | |
| SCHEMBL28125892 | 0.79 | SMN1; SMN2 (0.41) | HPGDSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL28298093 | 0.79 | HPGD (0.33) | HPGDSMN1; SMN2RECQLLMNA | |
| SCHEMBL27756610 | 0.78 | HTT (0.53) | HPGDSMN1; SMN2RECQLALDH1A1HTT | |
| SCHEMBL28309465 | 0.77 | RECQL (0.65) | HPGDSMN1; SMN2RECQLALDH1A1HTT | |
| SCHEMBL27980515 | 0.77 | CHRNB2 (0.59) | HPGDSMN1; SMN2RECQLALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110475777-A | For treating and preventing new pyrido [2,3-b] benzazolyl compounds of bacterium infection | HOFFMANN LA ROCHE | 2019-11-19 | — | — | CN | disclosed |