Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 3/20 | 0.40 |
| ▸ | NOS2 | P35228 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | NR5A1 | Q13285 | 4/20 | 0.33 |
| ▸ | NR5A2 | O00482 | 3/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27884019 | 0.74 | TAAR1 (0.37) | NOS1NOS2MEN1KMT2ATAAR1 | |
| SCHEMBL28825055 | 0.70 | CHRNB4 (0.33) | NOS1NOS2 | |
| SCHEMBL22546622 | 0.69 | NISCH (0.41) | NOS1NOS2 | |
| SCHEMBL22546693 | 0.69 | NISCH (0.41) | NOS1NOS2 | |
| SCHEMBL28752552 | 0.68 | NOS1 (0.45) | NOS1NOS2 | |
| SCHEMBL12601589 | 0.68 | MIF (0.46) | — | |
| SCHEMBL28653878 | 0.67 | MIF (0.45) | — | |
| Biphenyl SCHEMBL15347228 | 0.66 | ALDH1A1 (0.56) | TSHRGPR84MEN1ALDH1A1KMT2A | |
| SCHEMBL29437712 | 0.66 | NISCH (0.39) | NOS1NOS2ALDH1A1TAAR1 | |
| SCHEMBL11625470 | 0.66 | NOS1 (0.42) | NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109734643-B | Method for synthesizing pyrroline compound by catalyzing amino alcohol and enol with iron | 陕西师范大学 | 2021-05-14 | — | — | CN | disclosed |
| CN-109734643-A | The method that iron catalytic amino alcohol synthesizes pyrrolines with enol | 陕西师范大学 | 2019-05-10 | — | — | CN | disclosed |